LEADER 04335nam 22006255 450 001 9910253915003321 005 20200702001644.0 010 $a3-319-53880-2 024 7 $a10.1007/978-3-319-53880-8 035 $a(CKB)3710000001177745 035 $a(DE-He213)978-3-319-53880-8 035 $a(MiAaPQ)EBC4845056 035 $a(PPN)200514687 035 $a(EXLCZ)993710000001177745 100 $a20170421d2017 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aBiotechnology and Production of Anti-Cancer Compounds /$fedited by Sonia Malik 205 $a1st ed. 2017. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2017. 215 $a1 online resource (XV, 328 p. 53 illus., 36 illus. in color.) 311 $a3-319-53879-9 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aChapter 1 Medicinal Plants: Ethno-Uses to Biotechnology Era -- Chapter 2 How Plants Can Contribute to the Supply of Anti-Cancer Compounds -- Chapter 3 Cancer and Biotechnology: A Matchup that Should Never Slowdown -- Chapter 4 Plant Derived Compounds with Anti-Cancer Properties: From Folklore to Practice -- Chapter 5 Anticancer Drugs from Plants -- Chapter 6 Cambial Meristematic Cells: A Sustainable Platform for the Production of Plant-Derived Anti-Cancer Crugs -- Chapter 7 Family Fabaceae: A Boon for Cancer Therapy -- Chapter 8 Small Cells For Big Ideas: The Cytotoxic Podophyllotoxin And The Long Journey In Discovering Its Biosynthetic Pathway -- Chapter 9 Hairy Root Culture for the Production of Useful Secondary Metabolites -- Chapter 10 Edible Mushrooms and Their In Vitro Culture as a Source of Anticancer Compounds -- Chapter 11 Genomics and Artificial Intelligence Working Together in Drugs Discovery and Repositioning: The Advent of Adaptive Pharmacogenomics in Glioblastoma and Chronic Arterial Inflammation Therapies -- Chapter 12 A Multiscale Haemorheological Computer-based Model of Chronic Inflammation: an in-Depth Investigation of Erythrocytes-driven Flow Characteristics in Atheroma Development. 330 $aThis book discusses cancers and the resurgence of public interest in plant-based and herbal drugs. It also describes ways of obtaining anti-cancer drugs from plants and improving their production using biotechnological techniques. It presents methods such as cell culture, shoot and root culture, hairy root culture, purification of plant raw materials, genetic engineering, optimization of culture conditions as well as metabolic engineering with examples of successes like taxol, shikonin, ingenol mebutate and podophylotoxin. In addition, it describes the applications and limitations of large-scale production of anti-cancer compounds using biotechnological means. Lastly, it discusses future economical and eco-friendly strategies for obtaining anti-cancer compounds using biotechnology. 606 $aPlant breeding 606 $aCell culture 606 $aNatural resources 606 $aPharmacology 606 $aCancer$xResearch 606 $aPlant Breeding/Biotechnology$3https://scigraph.springernature.com/ontologies/product-market-codes/L24060 606 $aCell Culture$3https://scigraph.springernature.com/ontologies/product-market-codes/L16020 606 $aNatural Resources$3https://scigraph.springernature.com/ontologies/product-market-codes/U39000 606 $aPharmacology/Toxicology$3https://scigraph.springernature.com/ontologies/product-market-codes/B21007 606 $aCancer Research$3https://scigraph.springernature.com/ontologies/product-market-codes/B11001 615 0$aPlant breeding. 615 0$aCell culture. 615 0$aNatural resources. 615 0$aPharmacology. 615 0$aCancer$xResearch. 615 14$aPlant Breeding/Biotechnology. 615 24$aCell Culture. 615 24$aNatural Resources. 615 24$aPharmacology/Toxicology. 615 24$aCancer Research. 676 $a631.52 676 $a660.6 702 $aMalik$b Sonia$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910253915003321 996 $aBiotechnology and Production of Anti-Cancer Compounds$92110402 997 $aUNINA