LEADER 04863nam 22006375 450 001 9910253913803321 005 20200704084258.0 010 $a3-319-53150-6 024 7 $a10.1007/978-3-319-53150-2 035 $a(CKB)3710000001176685 035 $a(DE-He213)978-3-319-53150-2 035 $a(MiAaPQ)EBC4841607 035 $a(PPN)200512692 035 $a(EXLCZ)993710000001176685 100 $a20170413d2017 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aAsymmetric Cell Division in Development, Differentiation and Cancer$b[electronic resource] /$fedited by Jean-Pierre Tassan, Jacek Z. Kubiak 205 $a1st ed. 2017. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2017. 215 $a1 online resource (VI, 421 p. 96 illus., 81 illus. in color.) 225 1 $aResults and Problems in Cell Differentiation,$x0080-1844 ;$v61 311 $a3-319-53149-2 320 $aIncludes bibliographical references. 327 $a1 Modeling Asymmetric Cell Division in Caulobacter crescentus Using a Boolean Logic Approach -- 2 Spatiotemporal models of asymmetric cell division cycle in Caulobacter crescentus -- 3 Intrinsic and extrinsic determinants linking spindle pole fate, spindle polarity and asymmetric cell division in the budding yeast S. cerevisiae -- 4 Wnt signaling polarizes C. elegans asymmetric cell divisions during development -- 5 Asymmetric cell division in the one-cell C.elegans embryo: multiple steps to generate cell size asymmetry -- 6 Size matters: how C. elegans asymmetric divisions regulate apoptosis -- 7 The midbody and its remnant in cell polarization and asymmetric cell division -- 8 Drosophila melanogaster neuroblasts: a model for asymmetric stem cell divisions -- 9 Asymmetric divisions in oogenesis -- 10 Asymmetric localization and distribution of factors determining cell fate during early development of Xenopus laevis -- 11 Asymmetries in cell division, cell size and furrowing in the Xenopus laevis embryo -- 12 Asymmetric and unequal cell divisions in ascidian embryos -- 13 Asymmetries and symmetries in the mouse oocyte and zygote -- 14 Symmetry does not come for free ? cellular mechanisms to achieve a symmetric cell division -- 15 A Comparative Perspective on Wnt/?-catenin Signalling in Cell Fate Determination -- 16 Extracellular regulation of the mitotic spindle and fate determinants driving asymmetric cell division -- 17 Regulation of asymmetric cell division in mammalian neural stem and cancer precursor cells -- 18 Molecular programs underlying asymmetric stem cell division and their disruption in malignancy. 330 $aThis book provides readers with an overview of the frequent occurrence of asymmetric cell division. Employing a broad range of examples, it highlights how this mode of cell division constitutes the basis of multicellular organism development and how its misregulation can lead to cancer. To underline such developmental correlations, readers will for example gain insights into stem cell fate and tumor growth. In turn, subsequent chapters include descriptions of asymmetric cell division from unicellular organisms to humans in both physiological and pathological conditions. The book also illustrates the importance of this process for evolution and our need to understand the background mechanisms, offering a valuable guide not only for students in the field of developmental biology but also for experienced researchers from neighboring fields. 410 0$aResults and Problems in Cell Differentiation,$x0080-1844 ;$v61 606 $aCell cycle 606 $aEmbryology 606 $aStem cells 606 $aCancer research 606 $aCell Cycle Analysis$3https://scigraph.springernature.com/ontologies/product-market-codes/L16030 606 $aEmbryology$3https://scigraph.springernature.com/ontologies/product-market-codes/L18010 606 $aStem Cells$3https://scigraph.springernature.com/ontologies/product-market-codes/L16010 606 $aCancer Research$3https://scigraph.springernature.com/ontologies/product-market-codes/B11001 615 0$aCell cycle. 615 0$aEmbryology. 615 0$aStem cells. 615 0$aCancer research. 615 14$aCell Cycle Analysis. 615 24$aEmbryology. 615 24$aStem Cells. 615 24$aCancer Research. 676 $a570 702 $aTassan$b Jean-Pierre$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aKubiak$b Jacek Z$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910253913803321 996 $aAsymmetric Cell Division in Development, Differentiation and Cancer$92239790 997 $aUNINA