LEADER 04400nam 22006375 450 001 9910253911803321 005 20200701011953.0 010 $a94-024-1045-7 024 7 $a10.1007/978-94-024-1045-7 035 $a(CKB)3710000001127503 035 $a(DE-He213)978-94-024-1045-7 035 $a(MiAaPQ)EBC4834789 035 $a(PPN)199764638 035 $a(EXLCZ)993710000001127503 100 $a20170331d2017 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aTranslational Bioinformatics and Its Application /$fedited by Dong-Qing Wei, Yilong Ma, William C.S. Cho, Qin Xu, Fengfeng Zhou 205 $a1st ed. 2017. 210 1$aDordrecht :$cSpringer Netherlands :$cImprint: Springer,$d2017. 215 $a1 online resource (VIII, 437 p. 85 illus., 59 illus. in color.) 225 1 $aTranslational Medicine Research,$x2451-991X 300 $aIncludes index. 311 $a94-024-1043-0 327 $aDrug Discovery -- Translational Bioinformatics and Drug Discovery -- Translational Research in Drug Discovery and Development -- Exploring the Potential of Herbal Ligands towards Multidrug Resistant Bacterial Pathogens by Computational Drug Discovery -- The Progress of New Targets of Anti-HIV and Its Inhibitors -- Exploration of Drug Candidates Interacting on Amyloid-? Protofibrils for Alzheimer?s Disease -- Homology Modeling, Structure Based Pharmacophore Modeling, High Throughput Virtual Screening and Docking Studies of L-Type Calcium Channel for Cadmium Toxicity -- Natural Compounds Are Smart Player in Context to Anticancer Potential: An In Silico and In Vitro Advancement -- Genome Wide Association Studies -- A Survey of Bioinformatics Based Tools in RNA-Sequencing (RNA-Seq) Data Analysis -- Epigenetics and Its Role in Human Cancer -- Methods for Microbiome Analysis -- Pharmacogenomics: Clinical Perspective, Strategies and Challenges -- Computational Network Approaches and Their Applications for Complex Diseases -- Bioinformatics Applications in Clinical Microbiology -- Artificial Intelligence and Automatic Image Interpretation in Modern Medicine -- Computation in Medicine: Medical Image Analysis and Visualization. 330 $aThis book offers a detailed overview of translational bioinformatics together with real-case applications. Translational bioinformatics integrates the areas of basic bioinformatics, clinical informatics, statistical genetics and informatics in order to further our understanding of the molecular basis of diseases. By analyzing voluminous amounts of molecular and clinical data, it also provides clinical information, which can then be applied. Filling the gap between clinic research and informatics, the book is a valuable resource for human geneticists, clinicians, health educators and policy makers, as well as graduate students majoring in biology, biostatistics, and bioinformatics. 410 0$aTranslational Medicine Research,$x2451-991X 606 $aBioinformatics 606 $aHuman genetics 606 $aBiostatistics 606 $aHealth informatics 606 $aBioinformatics$3https://scigraph.springernature.com/ontologies/product-market-codes/L15001 606 $aHuman Genetics$3https://scigraph.springernature.com/ontologies/product-market-codes/B12008 606 $aBiostatistics$3https://scigraph.springernature.com/ontologies/product-market-codes/L15020 606 $aHealth Informatics$3https://scigraph.springernature.com/ontologies/product-market-codes/H28009 615 0$aBioinformatics. 615 0$aHuman genetics. 615 0$aBiostatistics. 615 0$aHealth informatics. 615 14$aBioinformatics. 615 24$aHuman Genetics. 615 24$aBiostatistics. 615 24$aHealth Informatics. 676 $a570.285 702 $aWei$b Dong-Qing$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aMa$b Yilong$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aCho$b William C.S$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aXu$b Qin$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aZhou$b Fengfeng$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910253911803321 996 $aTranslational Bioinformatics and Its Application$92215761 997 $aUNINA