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010   $a3-319-39406-1
024 7 $a10.1007/978-3-319-39406-0
035   $a(CKB)3710000000838018
035   $a(EBL)4654007
035   $a(DE-He213)978-3-319-39406-0
035   $a(MiAaPQ)EBC4654007
035   $a(PPN)194804615
035   $a(EXLCZ)993710000000838018
100   $a20160824d2016      u|         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aApoptosis in Cancer Pathogenesis and Anti-cancer Therapy $eNew Perspectives and Opportunities /$fedited by Christopher D. Gregory
205   $a1st ed. 2016.
210  1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2016.
215   $a1 online resource (260 p.)
225 1 $aAdvances in Experimental Medicine and Biology,$x0065-2598 ;$v930
300   $aIncludes index.
311   $a3-319-39404-5 
327   $aForeword -- Preface -- 1. Molecular Cell Biology of Apoptosis and Necroptosis in Cancer -- 2. Clearance of Dying Cells by Phagocytes: Mechanisms and Implications for Disease Pathogenesis -- 3. Micro-environmental Effects of Cell Death in Malignant Disease -- 4. Apoptotic Caspases in Promoting Cancer: Implications from Their Roles in Development and Tissue Homeostasis -- 5. Axl and Mer Receptor Tyrosine Kinases: Distinct and Non-overlapping Roles in Inflammation and Cancer? -- 6. Immunogenic Apoptotic Cell Death and Anti-cancer Immunity -- 7. Cancer Cell Death-inducing Radiotherapy ? Impact on Local Tumour Control, Tumour Cell Proliferation and Induction of Systemic Anti-tumour Immunity -- 8. Novel Approaches to Apoptosis-inducing Therapies -- 9. Killing Is Not Enough ? How Apoptosis Hijacks Tumor-associated Macrophages to Promote Cancer Progression -- Index.
330   $aThis book discusses properties of apoptosis and other cell death modalities in cancer pathogenesis and treatment. Its nine chapters discuss modulation of anti-tumor inflammatory and immune responses, effects on the tumor microenvironment, to strategies for improving pro-apoptotic therapies, mechanisms and implications for disease pathogenesis, axl and mer receptor tyrosine kinases, immunogenic apoptotic cell death and anti-cancer immunity and cancer cell death-inducing radiotherapy. This book places the onco-biology of apoptosis in clear and objective perspective through an expertly synthesized series of reviews. Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy is a deft and thorough exploration of cutting-edge research in apoptosis and anti-cancer mechanisms from basic biology to oncology. It highlights a rapidly growing field within cancer research and is essential reading for oncologists, biochemists and advanced graduate students alike.
410  0$aAdvances in Experimental Medicine and Biology,$x0065-2598 ;$v930
606   $aCancer research
606   $aApoptosis
606   $aMolecular biology
606   $aCancer Research$3https://scigraph.springernature.com/ontologies/product-market-codes/B11001
606   $aApoptosis$3https://scigraph.springernature.com/ontologies/product-market-codes/L16060
606   $aMolecular Medicine$3https://scigraph.springernature.com/ontologies/product-market-codes/B1700X
615  0$aCancer research.
615  0$aApoptosis.
615  0$aMolecular biology.
615 14$aCancer Research.
615 24$aApoptosis.
615 24$aMolecular Medicine.
676   $a610
702   $aGregory$b Christopher D$4edt$4http://id.loc.gov/vocabulary/relators/edt
906   $aBOOK
912   $a9910253903103321
996   $aApoptosis in Cancer Pathogenesis and Anti-cancer Therapy$92517337
997   $aUNINA