LEADER 03898nam 22007335 450 001 9910253898703321 005 20211215200605.0 010 $a1-4939-3450-3 024 7 $a10.1007/978-1-4939-3450-8 035 $a(CKB)3150000000021308 035 $a(EBL)4566601 035 $a(SSID)ssj0001653363 035 $a(PQKBManifestationID)16433502 035 $a(PQKBTitleCode)TC0001653363 035 $a(PQKBWorkID)14982349 035 $a(PQKB)10717778 035 $a(DE-He213)978-1-4939-3450-8 035 $a(MiAaPQ)EBC4566601 035 $a(PPN)192221264 035 $a(EXLCZ)993150000000021308 100 $a20160229d2016 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aCircadian Clocks: Role in Health and Disease /$fedited by Michelle L. Gumz 205 $a1st ed. 2016. 210 1$aNew York, NY :$cSpringer New York :$cImprint: Springer,$d2016. 215 $a1 online resource (382 p.) 225 1 $aPhysiology in Health and Disease,$x2625-252X 300 $aDescription based upon print version of record. 311 $a1-4939-3448-1 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aIntroduction and Mechanism of the Circadian Clock -- Circadian Rhythms in the Endocrine System -- Circadian Regulation of Sleep -- Circadian Rhythms in Neurological Disease -- Role of the Clock in Metabolism and Obesity -- Circadian Control of Renal Function -- Circadian Rhythms in the Vasculature -- The Cardiac Clock -- Regulation of Immunity by the Circadian Clock -- Rhythms in the Gastrointestinal System -- Chronotherapy in the Treatment of Cancer -- Chronotherapy in the Treatment of Hypertension.-The Circadian Clock as a Drug Target.-. 330 $aThis book sheds new light on the molecular mechanisms that generate circadian rhythms. It examines how biological rhythms influence physiological processes such as sleep, hormone synthesis and secretion, immunity, kidney function, the cardiovascular system, blood pressure, and the digestive system. Clinical implications are considered while exploring the impact of rhythms on neuropsychiatric disorders and chronotherapy?s potential for reducing cardiovascular risk. Offering a cross-section of expertise in both basic and translational (bench-to-bedside) research, this book serves as a guide for physicians and scientists who wish to learn more about the impact of circadian rhythms on physiological processes in health and disease. . 410 0$aPhysiology in Health and Disease,$x2625-252X 606 $aHuman physiology 606 $aMedical biochemistry 606 $aNephrology 606 $aCardiology 606 $aPsychiatry 606 $aHuman Physiology$3https://scigraph.springernature.com/ontologies/product-market-codes/B13004 606 $aMedical Biochemistry$3https://scigraph.springernature.com/ontologies/product-market-codes/H35005 606 $aNephrology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33126 606 $aCardiology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33037 606 $aPsychiatry$3https://scigraph.springernature.com/ontologies/product-market-codes/H53003 615 0$aHuman physiology. 615 0$aMedical biochemistry. 615 0$aNephrology. 615 0$aCardiology. 615 0$aPsychiatry. 615 14$aHuman Physiology. 615 24$aMedical Biochemistry. 615 24$aNephrology. 615 24$aCardiology. 615 24$aPsychiatry. 676 $a612.022 702 $aGumz$b Michelle L$4edt$4http://id.loc.gov/vocabulary/relators/edt 712 02$aAmerican Physiological Society (1887- ), 906 $aBOOK 912 $a9910253898703321 996 $aCircadian Clocks: Role in Health and Disease$92513545 997 $aUNINA