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010   $a981-10-1498-1
024 7 $a10.1007/978-981-10-1498-7
035   $a(CKB)3710000000746707
035   $a(DE-He213)978-981-10-1498-7
035   $a(MiAaPQ)EBC4584920
035   $a(PPN)194511995
035   $a(EXLCZ)993710000000746707
100   $a20160704d2016      u|         0
101 0 $aeng
135   $aurnn|008mamaa
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 14$aThe Long and Short Non-coding RNAs in Cancer Biology /$fedited by Erwei Song
205   $a1st ed. 2016.
210  1$aSingapore :$cSpringer Singapore :$cImprint: Springer,$d2016.
215   $a1 online resource (VIII, 458 p. 21 illus.) 
225 1 $aAdvances in Experimental Medicine and Biology,$x0065-2598 ;$v927
311   $a981-10-1496-5 
320   $aIncludes bibliographical references at the end of each chapters.
327   $aNon-coding RNAs: New Players in Cancers -- The Working Modules of Long Non-coding RNAs in Cancer Cells -- Methods to Study Long Non-coding RNA Biology in Cancer -- Relationship between Non-coding RNA Dysregulation and Epigenetic Mechanisms in Cancer -- Non-coding RNAs in Growth and Death of Cancer Cells -- Non-coding RNAs in Cancer Cell Plasticity -- Non-coding RNAs in Regulation of Cancer Metabolic Reprogramming -- Non-coding RNAs in Tumor Angiogenesis -- Non-coding RNAs in Cancer Immunity -- Non-coding RNAs in Therapeutic Resistance of Cancer -- Non-coding RNAs Regulating Cancer Signaling Network -- Non-coding RNAs Regulating NFkB Signaling -- Non-coding RNAs Regulating p53 and c-Myc Signaling -- Viral Non-coding RNAs in Cancer Biology -- Non-coding RNAs in Cancer Diagnosis -- Therapeutic Potentials of Non-coding RNAs: Targeted Delivery of NcRNAs in Cancer Cells.
330   $aThe book conveys a comprehensive knowledge of long and short ncRNAs in cancer regulation and their potentials as diagnostic biomarkers and therapeutic targets. Topics covered include the molecular mechanisms of various classes of ncRNAs (with emphasis on long non-coding RNAs and microRNAs) in cancer, the functional roles of ncRNAs in regulating different cancer hallmarks (including proliferation, apoptosis, stem-cell properties, epithelial-mesenchymal transition, metabolism, angiogenesis, tumor-host interactions and therapeutic resistance), the role of ncRNAs in regulating cancer signaling circuitry programs (highlighting their involvement in c-myc, p53 and NFkB signaling), a systemic summary of clinical and preclinical studies that evaluate the potential of ncRNA signatures for cancer diagnosis and prognosis and strategies to delivery short ncRNAs as therapeutic molecules for cancer treatment. This book may serve as a comprehensive resource for researchers, graduate students and oncologists in ncRNA and cancer research and help drug development by identifying ncRNA targets.
410  0$aAdvances in Experimental Medicine and Biology,$x0065-2598 ;$v927
606   $aCancer research
606   $aCell biology
606   $aCancer Research$3https://scigraph.springernature.com/ontologies/product-market-codes/B11001
606   $aCell Biology$3https://scigraph.springernature.com/ontologies/product-market-codes/L16008
615  0$aCancer research.
615  0$aCell biology.
615 14$aCancer Research.
615 24$aCell Biology.
676   $a616.994042
702   $aSong$b Erwei$4edt$4http://id.loc.gov/vocabulary/relators/edt
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910253897503321
996   $aThe Long and Short Non-coding RNAs in Cancer Biology$92541175
997   $aUNINA