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100   $a20160411d2016      u|         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 10$aHistophilus somni $eBiology, Molecular Basis of Pathogenesis, and Host Immunity /$fedited by Thomas J. Inzana
205   $a1st ed. 2016.
210  1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2016.
215   $a1 online resource (165 p.)
225 1 $aCurrent Topics in Microbiology and Immunology,$x0070-217X ;$v396
300   $aDescription based upon print version of record.
311   $a3-319-29554-3 
320   $aIncludes bibliographical references at the end of each chapters.
327   $aTaxonomy of Histophilus somni -- Histophilosis as a Natural Disease -- Histophilus somni Genomics and Genetics -- Interactions on Histophilus somni with Host Cells -- Histophilus somni Surface Proteins -- Host Immune Response to Histophilus somni -- The Many Facets of Lipooligosaccharide as a Virulence Factor of Histophilus somni -- Exopolysaccharide Production and Biofilm Formation by Histophilus somni.
330   $aThis volume reviews the current understanding of the taxonomy, disease syndromes, genetics, biology, and pathogenic factors of Histophilus somni, as well as the host immune response to this pathogen. H. somni is one of the most important bacterial pathogens in cattle and other ruminants, and its virulence factors are highly conserved with Haemophilus influenzae and other members of the Pasteurellaceae. H. somni has been recognized as a major cause of thrombotic meningoencephalitis, respiratory disease syndromes, myocarditis, reproductive disease syndromes, polyarthritis, mastitis, ocular disease, and septicemia. The only known habitats of H. somni are the mucosal surfaces of ruminants, making this bacterium an opportunistic pathogen. Although it is capable of causing inflammation at systemic sites and is toxic to epithelial and phagocytic cells, the bacterium?s wide array of virulence factors act primarily as a defense against, or to escape recognition from, host innate and adaptive immunity.
410  0$aCurrent Topics in Microbiology and Immunology,$x0070-217X ;$v396
606   $aMedical microbiology
606   $aVeterinary medicine
606   $aBacteriology
606   $aMedical Microbiology$3https://scigraph.springernature.com/ontologies/product-market-codes/B16003
606   $aVeterinary Medicine/Veterinary Science$3https://scigraph.springernature.com/ontologies/product-market-codes/H67000
606   $aBacteriology$3https://scigraph.springernature.com/ontologies/product-market-codes/L23012
615  0$aMedical microbiology.
615  0$aVeterinary medicine.
615  0$aBacteriology.
615 14$aMedical Microbiology.
615 24$aVeterinary Medicine/Veterinary Science.
615 24$aBacteriology.
676   $a636.0896014
702   $aInzana$b Thomas J$4edt$4http://id.loc.gov/vocabulary/relators/edt
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910253886403321
996   $aHistophilus somni$92527582
997   $aUNINA