LEADER 03399nam 22006975 450 001 9910253880503321 005 20230811000344.0 010 $a3-7091-1883-2 024 7 $a10.1007/978-3-7091-1883-2 035 $a(CKB)3880000000021667 035 $a(EBL)4200166 035 $a(SSID)ssj0001596861 035 $a(PQKBManifestationID)16297555 035 $a(PQKBTitleCode)TC0001596861 035 $a(PQKBWorkID)14886217 035 $a(PQKB)10117279 035 $a(DE-He213)978-3-7091-1883-2 035 $a(MiAaPQ)EBC4200166 035 $a(PPN)190880872 035 $a(EXLCZ)993880000000021667 100 $a20151218d2016 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aCongenital Heart Diseases: The Broken Heart $eClinical Features, Human Genetics and Molecular Pathways /$fedited by Silke Rickert-Sperling, Robert G. Kelly, David J. Driscoll 205 $a1st ed. 2016. 210 1$aVienna :$cSpringer Vienna :$cImprint: Springer,$d2016. 215 $a1 online resource (745 p.) 300 $aDescription based upon print version of record. 311 $a3-7091-1882-4 320 $aIncludes bibliographical references and index. 327 $aSection I: General introduction in cardiac development -- Section II: Different chapters covering the different types of congenital heart disease -- Section III: The overall perspective. 330 $aThis book provides comprehensive insights into congenital heart disease from embryonic development through to clinical features, including human genetics and our current knowledge of the underlying molecular pathways. It is divided into three parts: an introduction to the development of the heart and its vessels, an overview of the molecular pathways affecting the development of various cardiovascular structures, and a main section focusing on the different types of structural and nonstructural congenital heart diseases, including their clinical features, underlying genetic alterations and related animal models and pathways. Taken together these chapters, which were written by and for clinicians and researchers, provide an integrated and cutting-edge resource for all those who want to learn more about both the clinical aspects and the genetic and molecular basis of congenital heart disease. 606 $aMedicine$xResearch 606 $aBiology$xResearch 606 $aCardiology 606 $aDevelopmental biology 606 $aMedical genetics 606 $aBiomedical Research 606 $aCardiology 606 $aDevelopmental Biology and Stem Cells 606 $aMedical Genetics 615 0$aMedicine$xResearch. 615 0$aBiology$xResearch. 615 0$aCardiology. 615 0$aDevelopmental biology. 615 0$aMedical genetics. 615 14$aBiomedical Research. 615 24$aCardiology. 615 24$aDevelopmental Biology and Stem Cells. 615 24$aMedical Genetics. 676 $a610 702 $aRickert-Sperling$b Silke$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aKelly$b Robert G$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aDriscoll$b David J$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910253880503321 996 $aCongenital Heart Diseases: The Broken Heart$92494341 997 $aUNINA