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010   $a1-4939-3612-3
024 7 $a10.1007/978-1-4939-3612-0
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035   $a(SSID)ssj0001665634
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035   $a(PQKBTitleCode)TC0001665634
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035   $a(DE-He213)978-1-4939-3612-0
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100   $a20160429d2016      u|             0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 10$aMitochondria and Cell Death$b[electronic resource] /$fedited by David M. Hockenbery
205   $a1st ed. 2016.
210  1$aNew York, NY :$cSpringer New York :$cImprint: Humana,$d2016.
215   $a1 online resource (240 p.)
225 1 $aCell Death in Biology and Diseases,$x2625-2902
300   $aDescription based upon print version of record.
311   $a1-4939-3610-7 
320   $aIncludes bibliographical references at the end of each chapters and index.
327   $aPreface -- 1.Lethal and non-lethal functions of the permeability transition pore -- 2.Mitochondrial Calcium and Ischemia-Reperfusion Injury in Heart -- 3.Mislocalization of mitochondrial intermembrane space proteins -- 4.Bcl-2 protein interplay on the outer mitochondrial membrane -- 5.Remodeling of Mitochondria in Apoptosis -- 6.Physiologic and Pathologic Functions of Mitochondrial ROS -- 7.Mitochondrial Mutagenesis in Cancer -- 8.Mitochondrial UPR in cancer -- 9.Mitochondrial signaling -- 10.Mitochondria and antiviral immunity -- 11.Mitochondrial permeabilization from lethality to vitality -- Index.
330   $aThis volume examines the role of mitochondria in different types of cell death, including apoptotic and necrotic cell deaths. Topics discussed include mitochondrial outer membrane permeabilization (MOMP) and the permeability transition pore; core processes such as calcium handling, fission and fusion, reactive oxygen species generation, and maintenance of mitochondrial DNA fidelity and protein folding homeostasis; and retrograde signaling between mitochondria and other cellular components, including the important role of mitochondria in antiviral immunity. The expertly authored chapters are drawn from multidisciplinary international perspectives, lending a nuanced and comprehensive approach to the material. Mitochondria and Cell Death, part of the Cell Death in Biology and Diseases series, is invaluable reading for graduate students, researchers, and clinicians in the fields of neuroscience, oncology, gastroenterology, and hepatology, as well as those interested in the study of mitochondria and cell biology.
410  0$aCell Death in Biology and Diseases,$x2625-2902
606   $aApoptosis
606   $aCell membranes 
606   $aCell cycle
606   $aApoptosis$3https://scigraph.springernature.com/ontologies/product-market-codes/L16060
606   $aMembrane Biology$3https://scigraph.springernature.com/ontologies/product-market-codes/L16050
606   $aCell Cycle Analysis$3https://scigraph.springernature.com/ontologies/product-market-codes/L16030
615  0$aApoptosis.
615  0$aCell membranes .
615  0$aCell cycle.
615 14$aApoptosis.
615 24$aMembrane Biology.
615 24$aCell Cycle Analysis.
676   $a570
702   $aHockenbery$b David M$4edt$4http://id.loc.gov/vocabulary/relators/edt
906   $aBOOK
912   $a9910253871203321
996   $aMitochondria and Cell Death$92536185
997   $aUNINA