LEADER 03763nam 22006135 450 001 9910253869903321 005 20200704074543.0 010 $a3-319-32949-9 024 7 $a10.1007/978-3-319-32949-9 035 $a(CKB)3710000000657986 035 $a(EBL)4524958 035 $a(DE-He213)978-3-319-32949-9 035 $a(MiAaPQ)EBC4524958 035 $a(PPN)19407949X 035 $a(EXLCZ)993710000000657986 100 $a20160506d2016 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aHost Defense Peptides and Their Potential as Therapeutic Agents /$fedited by Richard M. Epand 205 $a1st ed. 2016. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2016. 215 $a1 online resource (323 p.) 300 $aDescription based upon print version of record. 311 $a3-319-32947-2 320 $aIncludes bibliographical references at the end of each chapters. 327 $aDiversity in Host Defense Antimicrobial Peptides -- Antifungal Host Defense Peptides -- Antiviral Host Defense Peptides -- Anticancer peptides: prospective innovation in cancer therapy -- Plant Antimicrobial Peptides -- Host Defense Peptides and the Eicosanoid Cascade -- Bacterial resistance to host defence peptides -- Engineered OAKs Against Antibiotic Resistance and for Bacterial Detection -- Structural Analysis of Amphibian, Insect and Plant Host Defense Peptides Inspires the Design of Novel Therapeutic Molecules -- How to teach old antibiotics new tricks -- Antimicrobial peptides and Preterm Birth -- Host defense peptides and their advancements in translational Staphylococcus aureus research.<. 330 $aThis book offers an overview of our current understanding of host defense peptides and their potential for clinical applications as well as some of the obstacles to this. The chapters, written by leading experts in the field, detail the number and diversity of host defense peptides, and discuss the therapeutic potential not only of antibacterial, but also of antifungal, antiviral, plant antimicrobial and anticancer host defense peptides. The authors provide new insights into their mechanisms of action and their immunomodulatory properties, and review recent advances in the design of novel therapeutic molecules. Lastly, their potential to prevent preterm births and Staphylococcus aureus infections is highlighted. The book is of interest to researchers, industry and clinicians alike. 606 $aProteins  606 $aImmunology 606 $aMicrobiology 606 $aMedical biochemistry 606 $aProtein Science$3https://scigraph.springernature.com/ontologies/product-market-codes/L14040 606 $aImmunology$3https://scigraph.springernature.com/ontologies/product-market-codes/B14000 606 $aApplied Microbiology$3https://scigraph.springernature.com/ontologies/product-market-codes/C12010 606 $aMedical Biochemistry$3https://scigraph.springernature.com/ontologies/product-market-codes/H35005 606 $aMicrobiology$3https://scigraph.springernature.com/ontologies/product-market-codes/L23004 615 0$aProteins . 615 0$aImmunology. 615 0$aMicrobiology. 615 0$aMedical biochemistry. 615 14$aProtein Science. 615 24$aImmunology. 615 24$aApplied Microbiology. 615 24$aMedical Biochemistry. 615 24$aMicrobiology. 676 $a570 702 $aEpand$b Richard M$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910253869903321 996 $aHost Defense Peptides and Their Potential as Therapeutic Agents$92523560 997 $aUNINA