LEADER 03601nam 22006615 450 001 9910253869403321 005 20200706112407.0 010 $a94-017-7417-X 024 7 $a10.1007/978-94-017-7417-8 035 $a(CKB)3710000000533053 035 $a(EBL)4189957 035 $a(SSID)ssj0001596886 035 $a(PQKBManifestationID)16297933 035 $a(PQKBTitleCode)TC0001596886 035 $a(PQKBWorkID)14885434 035 $a(PQKB)10123236 035 $a(DE-He213)978-94-017-7417-8 035 $a(MiAaPQ)EBC4189957 035 $a(PPN)190885394 035 $a(EXLCZ)993710000000533053 100 $a20151211d2016 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aNon-coding RNA and the Reproductive System /$fedited by Dagmar Wilhelm, Pascal Bernard 205 $a1st ed. 2016. 210 1$aDordrecht :$cSpringer Netherlands :$cImprint: Springer,$d2016. 215 $a1 online resource (201 p.) 225 1 $aAdvances in Experimental Medicine and Biology,$x0065-2598 ;$v886 300 $aDescription based upon print version of record. 311 $a94-017-7415-3 320 $aIncludes bibliographical references at the end of each chapters and index. 330 $aThis book provides an overview of the role and function of regulatory RNAs that lack protein-coding potential in key reproductive tissues. This includes the role of small interfering RNAs (siRNAs), microRNAs (miRNAs), PIWI-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs) and long non-coding RNAs (lncRNAs). Through clear, detailed and comprehensive debate, international leading experts discuss the role these novel regulators in normal development of sexual dimorphisms, including the differentiation of ovaries and testes, the genital tract including prostate, epididymis and uterus, as well as mammary glands. In addition, particular attention is paid on their role in pathophysiological processes within the reproductive tract. The power of next generation sequencing has proved to be an invaluable tool to discover new non-coding RNAs. While the identification of non-coding RNA is relatively easy, analysing their function represents still a challenge today. In this book, authors present historical and conceptual background information, highlight the ways in which non-coding RNAs function is analysed and present their vision of the future research in their key research area. 410 0$aAdvances in Experimental Medicine and Biology,$x0065-2598 ;$v886 606 $aMedical genetics 606 $aDevelopmental biology 606 $aReproductive medicine 606 $aGene Function$3https://scigraph.springernature.com/ontologies/product-market-codes/B12030 606 $aDevelopmental Biology$3https://scigraph.springernature.com/ontologies/product-market-codes/L18000 606 $aReproductive Medicine$3https://scigraph.springernature.com/ontologies/product-market-codes/H56002 615 0$aMedical genetics. 615 0$aDevelopmental biology. 615 0$aReproductive medicine. 615 14$aGene Function. 615 24$aDevelopmental Biology. 615 24$aReproductive Medicine. 676 $a572.88 702 $aWilhelm$b Dagmar$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aBernard$b Pascal$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910253869403321 996 $aNon-coding RNA and the Reproductive System$92529381 997 $aUNINA