LEADER 03912nam 22005535 450 001 9910253868103321 005 20251116155503.0 010 $a3-319-35098-6 024 7 $a10.1007/978-3-319-35098-1 035 $a(CKB)3710000000717858 035 $a(EBL)4530186 035 $a(DE-He213)978-3-319-35098-1 035 $a(MiAaPQ)EBC4530186 035 $a(PPN)194074404 035 $a(EXLCZ)993710000000717858 100 $a20160519d2016 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aAdvances in Respiratory Cancerogenesis /$fedited by Mieczyslaw Pokorski 205 $a1st ed. 2016. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2016. 215 $a1 online resource (94 p.) 225 1 $aNeuroscience and Respiration ;$v911 300 $aDescription based upon print version of record. 311 08$a3-319-35097-8 320 $aIncludes bibliographical references and index. 327 $aChapter 1. The Role of Dysregulated MicroRNA Expression in Lung Cancer -- Chapter 2. Laryngeal Cancer: 12-Year Experience of a Single Center -- Chapter 3. Polymorphisms of Selected DNA Repair Genes and Lung Cancer in Chromium Exposure -- Chapter 4. Associations of CYP1A2 Polymorphisms with the Risk Haplotypes in Lung Cancer in the Slovak Population -- Chapter 5. Diagnostic Yield of Endobronchial Ultrasound Guided Transbronchial Needle Aspiration in Patients with Mediastinal Lymph Node Enlargement. - Chapter 6. The Effect on Cognition of Mitochondrial Respiratory System Proteins in Peripheral Blood Mononuclear Cells in the Course of Lung Cancer -- Chapter 7. Lung Cancer and Multiple Neoplasms: a Retrospective Analysis -- Chapter 8. Humoral Immune Response against Neural Antigens and its Effects on Cognition in Lung Cancer Patients. ? Chapter 9. Active Case Finding Among Homeless People as a Means of Reducing the Incidence of Pulmonary Tuberculosis in General Population -- Chapter 10. Cryptogenic Organizing Pneumonia: IL-1?, IL-6, IL-8, and TGF- ?1 Serum Concentrations and Response to Clarithromycin Treatment. . 330 $aLung cancer is the leading cause of mortality worldwide, with a low survival rate. Carcinogenesis generally requires a constellation of entwined steps, involving both innate cellular and environmental factors. This book shares the updated knowledge on the origin and development of cancer through genotypic changes which upset the physiological balance between cell proliferation, differentiation, growth control, and apoptosis. The emphasis is put on the role of microRNA proteins involved in the cellular processes above outlined. Cognitive changes, related to dysregulated cellular mechanisms in cancer cells, as yet unchartered area of research, also are tackled. A better understanding of the molecular and cellular biology of lung cancer is the key source of breakthroughs in the diagnosis and prognosis, and finding more effective therapies that target specific mutations. The book provides a source of current facts and trends in clinical research and practice. It will be of interest to clinicians, researchers, and other medical professionals. . 410 0$aNeuroscience and Respiration ;$v911 606 $aCancer$xResearch 606 $aRespiratory organs?Diseases 606 $aCytology 606 $aRespiratory Tract Neoplasms 615 0$aCancer$xResearch. 615 0$aRespiratory organs?Diseases. 615 0$aCytology. 615 12$aRespiratory Tract Neoplasms. 676 $a616.994 702 $aPokorski$b Mieczyslaw$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910253868103321 996 $aAdvances in Respiratory Cancerogenesis$92503135 997 $aUNINA