LEADER 03437nam 22006495 450 001 9910253867203321 005 20200705033315.0 010 $a3-319-33145-0 024 7 $a10.1007/978-3-319-33145-4 035 $a(CKB)3710000000649253 035 $a(EBL)4513933 035 $a(SSID)ssj0001665611 035 $a(PQKBManifestationID)16455476 035 $a(PQKBTitleCode)TC0001665611 035 $a(PQKBWorkID)15000313 035 $a(PQKB)11612035 035 $a(DE-He213)978-3-319-33145-4 035 $a(MiAaPQ)EBC4513933 035 $a(iGPub)SPNA0044191 035 $a(PPN)193445549 035 $a(EXLCZ)993710000000649253 100 $a20160423d2016 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aAutophagy at the Cell, Tissue and Organismal Level /$fby Eleftherios Karanasios, Nicholas T. Ktistakis 205 $a1st ed. 2016. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2016. 215 $a1 online resource (107 p.) 225 1 $aSpringerBriefs in Cell Biology,$x2625-3534 300 $aDescription based upon print version of record. 311 $a3-319-33143-4 320 $aIncludes bibliographical references at the end of each chapters. 327 $aAutophagy (Autophagia) from 1860 to 1963 -- History of Autophagy after 1963 -- Signalling in Autophagy -- Autophagosome Formation -- Physiological Role of Autophagy and Implications in Disease -- Studying autophagy: List of useful antibodies produced via a community effort. 330 $aThis book provides an expert summary of autophagy, a relatively new but rapidly expanding field of biomedical science with important implications in health and disease. After a historical review ranging up to the identification of autophagy genes in mammals, the authors discuss the signaling pathways that regulate autophagy, the mechanism of autophagosome formation and the physiological roles of autophagy in development, ageing, neurodegeneration, immune function and cell differentiation. A comprehensive list of useful antibodies for studying autophagy compiled as a community effort is included at the end. The book is intended for newcomers to the field, as well as more experienced researchers looking for a condensed but comprehensive introduction to the physiological function and regulation of the autophagic pathway in mammalian organisms. 410 0$aSpringerBriefs in Cell Biology,$x2625-3534 606 $aCell biology 606 $aImmunology 606 $aBiochemistry 606 $aCell Biology$3https://scigraph.springernature.com/ontologies/product-market-codes/L16008 606 $aImmunology$3https://scigraph.springernature.com/ontologies/product-market-codes/B14000 606 $aAnimal Biochemistry$3https://scigraph.springernature.com/ontologies/product-market-codes/L14013 615 0$aCell biology. 615 0$aImmunology. 615 0$aBiochemistry. 615 14$aCell Biology. 615 24$aImmunology. 615 24$aAnimal Biochemistry. 676 $a570 700 $aKaranasios$b Eleftherios$4aut$4http://id.loc.gov/vocabulary/relators/aut$01062224 702 $aKtistakis$b Nicholas T$4aut$4http://id.loc.gov/vocabulary/relators/aut 906 $aBOOK 912 $a9910253867203321 996 $aAutophagy at the Cell, Tissue and Organismal Level$92523557 997 $aUNINA