LEADER 05965nam 22007095 450 001 9910253861003321 005 20200704114340.0 010 $a94-007-6419-7 024 7 $a10.1007/978-94-007-6419-4 035 $a(CKB)3710000000627615 035 $a(SSID)ssj0001656769 035 $a(PQKBManifestationID)16440450 035 $a(PQKBTitleCode)TC0001656769 035 $a(PQKBWorkID)14986402 035 $a(PQKB)10984243 035 $a(DE-He213)978-94-007-6419-4 035 $a(MiAaPQ)EBC5592590 035 $a(PPN)192770284 035 $a(EXLCZ)993710000000627615 100 $a20160321d2016 u| 0 101 0 $aeng 135 $aurnn#008mamaa 181 $ctxt 182 $cc 183 $acr 200 10$aMarine and Freshwater Toxins /$fedited by P. Gopalakrishnakone, Vidal Haddad Jr., Aurelia Tubaro, Euikyung Kim, William R. Kem 205 $a1st ed. 2016. 210 1$aDordrecht :$cSpringer Netherlands :$cImprint: Springer,$d2016. 215 $a1 online resource (121 illus., 91 illus. in color. eReference.) 225 1 $aToxinology,$x2542-761X 300 $aBibliographic Level Mode of Issuance: Monograph 311 $a94-007-6420-0 311 $a94-007-6418-9 320 $aIncludes bibliographical references and index. 327 $aPhylum Porifera and Cnidaria -- Clinical and Therapeutic Aspects of Envenomations Caused by Sponges and Jellyfish -- Phyla Molluska: The Venom Apparatus of Cone Snails -- Venomous Marine Fish: Evolution of the Venoms. Condrichthyes (Cartilaginous Fish) -- Venomous Marine Fish: Osteicthyes (Bony Fish) -- Venomous Freshwater Fish: Catfish and Freshwater Stingrays -- Toxins Produced by Marine Microorganisms: A Short Review -- Toxins Produced by Marine Invertebrate and Vertebrate Animals: A Short Review -- Pufferfish Poisoning and Tetrodotoxin -- Ciguatoxin and Ciguatera -- Saxitoxin and Other Paralytic Toxins: Toxicological Profile -- Brevetoxins: Toxicological Profile -- Okadaic Acid and Other Diarrheic Toxins: Toxicological Profile -- Domoic Acid and Other Amnesic Toxins: Toxicological Profile -- Azaspiracid Toxins: Toxicological Profile -- Spirolides and Cyclic Imines: Toxicological Profile -- Palytoxins: Toxicological Profile -- Effects of Cyanotoxins: Sea and Freshwater Toxins -- Microcystins: Toxicological Profile -- Jellyfish Venom and Toxins : A Review -- Equinatoxins: A Review -- Intoxications Caused by Saxitoxin, Shellfish, and Other Neurotoxins -- Phylum Echinodermata e Annelida: Sea Urchins, Starfish and Sea Cucumbers, and Marine Worms -- Instrumental Methods for Paralytic Shellfish Toxins -- Immunomodulatory Properties of Sea Cucumber Triterpene Glycosides -- Miscellaneous Marine Toxins of Medical Significance. . 330 $aThis book presents the structure of the main toxins of aquatic origin, their distribution, producing species and vectors, their mechanisms of action, the clinical aspects of envenomation in humans, their effects in laboratory or wild animals, their toxicokinetic properties, including the relevant treatment, detection methods and regulatory aspects for management. The work also presents the main species associated with the injuries, poisonings their toxins, mechanism of action and the clinical aspects of the envenomations by aquatic animals and discusses the actual measures utilized in the first aid and hospital treatments. Marine toxins such as palytoxins, brevetoxins, saxitoxin, ciguatoxins, okadaic acid, azaspiracid toxins, equinatoxins are also dealt with in this volume. These toxins can be lethal as well as having a complex and large molecular structure and display mechanisms by which they act very specifically on targets, receptors or on critical body proteins. The marine and freshwater environments are the new frontiers of humanity, but the increase of economic and tourist activities provoke nasty encounters between aquatic animals and humans. The main victims are swimmers, professional and sportive fishermen, surfers and scuba divers as well as people working in related fields. The identification, knowledge and treatment of envenomations caused by venomous and poisonous animals are not adequate and the prevention of injuries still is not possible. Additionally, the immense potential of the pharmacologic effects of their toxins is not fully explored. Toxins of venomous aquatic animals can cause proteolysis, myotoxicity, hemotoxicity (mainly hemolysis), cytotoxicity and neurotoxicity. The neurotoxicity is generally associated with toxins of dinoflagellates and cyanobacteria, present in poisonous and/or contaminated invertebrates and fish. 410 0$aToxinology,$x2542-761X 606 $aPharmaceutical technology 606 $aBiochemistry 606 $aAnimal physiology 606 $aPharmaceutical Sciences/Technology$3https://scigraph.springernature.com/ontologies/product-market-codes/B21010 606 $aAnimal Biochemistry$3https://scigraph.springernature.com/ontologies/product-market-codes/L14013 606 $aAnimal Physiology$3https://scigraph.springernature.com/ontologies/product-market-codes/L33030 615 0$aPharmaceutical technology. 615 0$aBiochemistry. 615 0$aAnimal physiology. 615 14$aPharmaceutical Sciences/Technology. 615 24$aAnimal Biochemistry. 615 24$aAnimal Physiology. 676 $a615.19 702 $aGopalakrishnakone$b P$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aHaddad Jr$b Vidal$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aTubaro$b Aurelia$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aKim$b Euikyung$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aKem$b William R$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910253861003321 996 $aMarine and Freshwater Toxins$92495842 997 $aUNINA