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001 9910253860903321
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010   $a3-319-27347-7
024 7 $a10.1007/978-3-319-27347-1
035   $a(CKB)3710000000616284
035   $a(EBL)4452729
035   $a(OCoLC)945613280
035   $a(SSID)ssj0001653366
035   $a(PQKBManifestationID)16433198
035   $a(PQKBTitleCode)TC0001653366
035   $a(PQKBWorkID)14982712
035   $a(PQKB)10235240
035   $a(DE-He213)978-3-319-27347-1
035   $a(MiAaPQ)EBC4452729
035   $a(PPN)192774166
035   $a(EXLCZ)993710000000616284
100   $a20160315d2016      u|         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 10$aClinical Pharmacology: Current Topics and Case Studies /$fedited by Markus Müller
205   $a2nd ed. 2016.
210  1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2016.
215   $a1 online resource (398 p.)
300   $aDescription based upon print version of record.
311   $a3-319-27345-0 
320   $aIncludes bibliographical references and index.
327   $aThe discipline of Clinical Pharmacology -- Current issues in drug development -- Current issues in drug regulation -- Current issues in drug reimbursement -- Ethics of clinical research -- GCP, Scientific misconduct -- Phases of drug development, first in man studies -- Clinical trials - Interventional studies -- Clinical trials - observational studies -- Imaging -- Microdosing -- Genomics -- Pharmacokinetics/Pharmacodynamics -- Epidemiology, statistics -- Placebo effects -- Pharmaceutical drug safety -- Drug interactions -- Advanced therapies -- Biological pharmaceuticals -- Generic drugs, Enantiomers -- Special situations I: orphan drugs -- Special situations II: sex differences -- Special situations III: children.
330   $aThis revised and extended second edition focuses on current and emerging topics in drug development, their molecular mechanisms of action as well as regulatory issues. In addition, in-depth insights into clinical drug research and trial methodology are presented on the basis of concrete case studies. This updated book makes a valuable contribution to the field of Clinical Pharmacology and serves as a must-have guide for professors, researchers and advanced students from academia and pharmaceutical industry. .
606   $aPharmacology
606   $aPharmacy
606   $aPharmacotherapy
606   $aPharmacology/Toxicology$3https://scigraph.springernature.com/ontologies/product-market-codes/B21007
606   $aPharmacy$3https://scigraph.springernature.com/ontologies/product-market-codes/F00008
606   $aPharmacotherapy$3https://scigraph.springernature.com/ontologies/product-market-codes/H69000
615  0$aPharmacology.
615  0$aPharmacy.
615  0$aPharmacotherapy.
615 14$aPharmacology/Toxicology.
615 24$aPharmacy.
615 24$aPharmacotherapy.
676   $a610
702   $aMüller$b Markus$4edt$4http://id.loc.gov/vocabulary/relators/edt
906   $aBOOK
912   $a9910253860903321
996   $aClinical Pharmacology: Current Topics and Case Studies$92526692
997   $aUNINA