LEADER 02330nam 2200433 450 001 9910251430103321 005 20231214145441.0 010 $a953-51-4800-1 010 $a953-51-3196-6 035 $a(CKB)4100000001586729 035 $a(iGPub)INOP0001891 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/58595 035 $a(EXLCZ)994100000001586729 100 $a20200302017 xx c0 0 101 0 $aeng 135 $aurcn||||m|||a 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aRole of neutrophils in disease pathogenesis 210 $cIntechOpen$d2017 210 1$a[Place of publication not identified] :$cIntechOpen,$d2017. 210 4$dİ2017 215 $a1 online resource (182 pages) 311 $a953-51-3195-8 330 $aThis book highlights the important role of neutrophils in health as well as in the pathogenesis of various diseases. Section 1 provides a general background information regarding the mechanisms and various triggers of neutrophil extracellular traps (NETs) formation and their role in various infectious and noninfectious diseases (such as postinjury inflammation). Section 2 provides recent evidence regarding the role of neutrophils in the pathogenesis as well as a therapeutic target for selected disease conditions such as periodontal diseases, rheumatoid arthritis, and cystic fibrosis. Section 3 describes the anti-inflammatory properties of neutrophils with focus regarding their role in graft versus host disease. This book provides a wider picture with regard to the importance of this immune cell type in various diseases with focus on one of its recently discovered properties, NETs. Therapeutic targets aimed to modulate neutrophil functions might provide novel approaches in the treatment of various diseases of infectious and noninfectious origin. 606 $aMEDICAL / Hematology$2bisacsh 610 $aMedicine 610 $aHematology 610 $aHemorheology 610 $aHealth Sciences 615 7$aMEDICAL / Hematology. 676 $a616 700 $aMaitham Abbas Khajah$4auth$01328798 702 $aKhajah$b Maitham Abbas 906 $aBOOK 912 $a9910251430103321 996 $aRole of neutrophils in disease pathogenesis$93038964 997 $aUNINA