LEADER 02659nam  2200385z- 450 
001 9910227347503321
005 20210211
035   $a(CKB)4100000000883858
035   $a(oapen)https://directory.doabooks.org/handle/20.500.12854/48671
035   $a(oapen)doab48671
035   $a(EXLCZ)994100000000883858
100   $a20202102d2017      |y         0
101 0 $aeng
135   $aurmn|---annan
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 00$aThe Global Challenge Posed by the Multiresistant International Clones of Bacterial Pathogens
210   $cFrontiers Media SA$d2017
215   $a1 online resource (291 p.)
225 1 $aFrontiers Research Topics
311 08$a2-88945-217-4 
330   $aMultiresistant bacterial pathogens pose a serious problem worldwide making the appropriate treatment of patients with healthcare-associated infections a challenge. The spread of antibiotic resistance is either mediated by mobile genetic elements (MGEs) or the dissemination of genetically-related groups of pathogens, "high-risk clonal complexes". Interestingly most multiresistant healthcare-associated bacteria command just a few dominant international clonal complexes causing infections in various geographical areas. It is of utmost importance to identify the determinants associated with and promoting the spread of antibiotic resistance and the dissemination of these multiresistant pathogens. The Topic comprises mostly of population and epidemiological studies investigating antibiotic resistance mechanisms, MGEs and the impact of antibiotic resistance, and the production of virulence factors on the clonal dynamics of a diverse range of bacterial species. Though, the exploration of the mechanisms governing clonal dynamics and the dissemination of antibiotic resistance will remain a salient issue for a considerable time to come we believe that the papers published in the Topic have usefully contributed to the better understanding of some of the processes involved and supplement papers investigating the "non-bacterial" constituents of clonal mobility, like proper medical practice and compliance with hygienic standards.
606   $aMicrobiology (non-medical)$2bicssc
610   $aantibiotic resistance
610   $aClone
610   $adissemination
610   $apathogen
615  7$aMicrobiology (non-medical)
700   $aMiklos Fuzi$4auth$01292555
702   $aMargaret Ip$4auth
906   $aBOOK
912   $a9910227347503321
996   $aThe Global Challenge Posed by the Multiresistant International Clones of Bacterial Pathogens$93022388
997   $aUNINA