LEADER 03688nam 2200421z- 450 001 9910220059403321 005 20231214133639.0 035 $a(CKB)3800000000216184 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/48153 035 $a(EXLCZ)993800000000216184 100 $a20202102d2016 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aFrontiers in Brain Based Therapeutic Interventions and Biomarker Research in Child and Adolescent Psychiatry 210 $cFrontiers Media SA$d2016 215 $a1 electronic resource (107 p.) 225 1 $aFrontiers Research Topics 311 $a2-88919-954-1 330 $aDevelopmental neuroscience research is on the cusp of unprecedented advances in the understanding of how variations in brain structure and function within neural circuits confer risk for symptoms of childhood psychiatric disorders. Novel dimensional approaches to illness classification, the availability of non-invasive, diverse and increasingly sophisticated methods to measure brain structure and function in humans in vivo, and advances in genetics, animal model and multimodal research now place brain-based biomarkers within reach in the field of psychiatry. These advances hold great promise for moving neuroscience research into the clinical realm. One exciting new area of translational research in child and adolescent psychiatry, is in the use of a variety of neuroscience research tools to track brain response to clinical intervention. Examples of this include: using longitudinal neuroimaging techniques to track changes in white matter microstructure following a training intervention for children with poor reading skills, or using functional imaging to compare brain activity before and after children with bipolar disorder begin taking psychotropic medication treatment. Brain stimulation is another cutting-edge research area where brain response to therapeutic intervention can be closely tracked with electroencephalography or other brain imaging modalities. Research using neuroscience tools to track brain response to clinical interventions is beginning to yield novel insights into the etiopathogenesis of psychiatric illness, and is providing preliminary feedback around how therapeutic interventions work in the brain to bring about symptom improvement. Using these novel approaches, neuroscience research may soon move into the clinical realm to target early pathophysiology, and tailor treatments to both individuals and specific neurodevelopmental trajectories, in an effort to alter the course of development and mitigate risk for a lifetime of morbidity and ineffective treatments. Excitement and progress in these areas must be tempered with safety and ethical considerations for these vulnerable populations. This research topic focuses on efforts to use neuroscience research tools to identify brain-based biomarkers of therapeutic response in child and adolescent psychiatry. 610 $aEating Disorders 610 $aNeuroimaging 610 $aAffective Disorders 610 $aBrain Stimulation 610 $aBipolar Disorder 610 $aChild Psychiatry 610 $abiomarkers 610 $achild and youth mental health 610 $aNeurodevelopmental disorders 610 $aautism 700 $aStephanie H. Ameis$4auth$01311553 702 $aPaul E. Croarkin$4auth 906 $aBOOK 912 $a9910220059403321 996 $aFrontiers in Brain Based Therapeutic Interventions and Biomarker Research in Child and Adolescent Psychiatry$93030414 997 $aUNINA