LEADER 02578nam 2200445z- 450 001 9910220051103321 005 20231214133656.0 035 $a(CKB)3800000000216266 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/48212 035 $a(EXLCZ)993800000000216266 100 $a20202102d2017 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aFungal Jewels: Secondary Metabolites 210 $cFrontiers Media SA$d2017 215 $a1 electronic resource (203 p.) 225 1 $aFrontiers Research Topics 311 $a2-88945-136-4 330 $aFungal natural products are friends and foes of humans such as deleterious mycotoxins, cytotoxic, carcinogenic compounds or beneficial compounds such as antibiotics, fungicides, insecticides, antiviral and antitumor metabolites. Understanding fungal diversity and estimation of fungal species on our planet poses a great challenge to researchers. This complexity is further multiplied by secondary metabolite diversity of fungi, which requires interdisciplinary studies. It is extremely important to understand the fungal secondary metabolism to stop human, animal and plant diseases caused by fungi and harvest their valuable metabolites. Furthermore, many secondary metabolite gene clusters are silenced under laboratory conditions. It is vital to develop effective methods to activate those clusters in order to discover novel potent metabolites. This e-book is a compilation of original review articles contributed by leading fungal secondary metabolite researchers with a wide range of expertise. Important aspects of fungal secondary metabolism, including regulation, genome mining, evolution, synthetic biology and novel methods have been discussed. This book will be a great source to those people, who are interested in understanding overall structure, diversity and regulation of production of these tiny but precious chemicals. 517 $aFungal Jewels 610 $aFungi 610 $amushrooms 610 $aNatural Products 610 $asilent clusters 610 $aGene clusters 610 $asecondary metabolism 610 $aMycotoxins 610 $aMolds 610 $aantibiotics 610 $agenome mining 700 $aOzgur Bayram$4auth$01312906 702 $aNancy Keller$4auth 702 $aJonathan Palmer$4auth 906 $aBOOK 912 $a9910220051103321 996 $aFungal Jewels: Secondary Metabolites$93031107 997 $aUNINA