LEADER 02974nam 2200445z- 450 001 9910220050003321 005 20210211 035 $a(CKB)3800000000216277 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/54490 035 $a(oapen)doab54490 035 $a(EXLCZ)993800000000216277 100 $a20202102d2016 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aNeuroanatomy for the XXIst Century 210 $cFrontiers Media SA$d2016 215 $a1 online resource (199 p.) 225 1 $aFrontiers Research Topics 311 08$a2-88919-916-9 330 $aAn explosion of new techniques with vastly improved visualization and sensitivity is leading a veritable revolution in modern neuroanatomy. Basic questions related to cell types, input localization, and connectivity are being re-visited and tackled with significantly more accurate and higher resolution experimental approaches. A major goal of this e-Book is thus to highlight in one place the impressive range of available techniques, even as these are fast becoming routine. This is not meant as a technical review, however, but rather will project the technical explosion as indicative of a field now in a vibrant state of renewal. Thus, contributions will be mainly research articles using the newer techniques. A second goal is to showcase what has become the conspicuous interdisciplinary reach of the field: neuroanatomical standards and the close association of structure-function and underlying circuitry mechanisms are increasingly relevant to investigations in development, physiology, and disease. Another feature of this Research Topic is that it includes a breadth of cross-species contributions from investigators working with rodent, nonhuman primate, and human brains. This is important since most of our current knowledge of brain structure has been obtained from experimental animals. However, recent technical advances, coupled with researcher willingness to use the human tissue available, will undoubtedly lead to major advances in the near future regarding human brain mapping and connectomes. Thus, of particular interest will be the methods that can help to define general wiring principles in the brain, both structural and functional. Overall, the state of the field is: exciting. 606 $aNeurosciences$2bicssc 610 $aFIB/SEM 610 $afMOST 610 $aHuman neuroanatomy 610 $alight-sheet imaging 610 $aPolarized light microscopy 610 $asynaptic weights 610 $atext-mining 610 $atwo-photon tomography 610 $aviral vectors 615 7$aNeurosciences 700 $aKathleen S. Rockland$4auth$01325378 702 $aJavier DeFelipe$4auth 906 $aBOOK 912 $a9910220050003321 996 $aNeuroanatomy for the XXIst Century$93036820 997 $aUNINA