LEADER 03817nam 2201153z- 450 001 9910576872703321 005 20220621 035 $a(CKB)5720000000008449 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/84525 035 $a(oapen)doab84525 035 $a(EXLCZ)995720000000008449 100 $a20202206d2022 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aPhylogenomic, Biogeographic, and Evolutionary Research Trends in Arachnology 210 $aBasel$cMDPI - Multidisciplinary Digital Publishing Institute$d2022 215 $a1 online resource (256 p.) 311 08$a3-0365-4165-9 311 08$a3-0365-4166-7 330 $aThis book focuses on systematics, biogeography, and evolution of arachnids, a group of ancient chelicerate lineages that have taken on terrestrial lifestyles. The book opens with the questions of what arachnology represents, and where the field should go in the future. Twelve original contributions then dissect the current state-of-the-art in arachnological research. These papers provide innovative phylogenomic, evolutionary and biogeographic analyses and interpretations of new data and/or synthesize our knowledge to offer new directions for the future of arachnology. 606 $aBiology, life sciences$2bicssc 606 $aMicrobiology (non-medical)$2bicssc 606 $aResearch & information: general$2bicssc 610 $aancestral range analysis 610 $aarachnid 610 $aArachnida 610 $aaraneae 610 $aAraneae 610 $aArthropoda 610 $abiodiversity 610 $aBioGeoBEARS 610 $abiogeography 610 $aCaatinga 610 $aCaribbean biogeography 610 $acerebrum 610 $acircular reasoning 610 $acoin spider 610 $acommunity ecology 610 $adata management 610 $adeep phylogeny 610 $adispersal 610 $adispersal probability 610 $adistribution 610 $adivergence time 610 $adiversity 610 $adynamic disperser 610 $aelevation 610 $aendemics 610 $afounder-event 610 $aGAARlandia 610 $aGalapagos 610 $aimaging 610 $aintermediate dispersal model 610 $aintermediate dispersal model of biogeography 610 $ainvestigator bias 610 $aLinyphiidae 610 $along distance dispersal 610 $aMicrathena 610 $amicro-CT 610 $amolecular dating 610 $amolecular phylogeny 610 $amonographic research 610 $an/a 610 $aNeotropical 610 $aNephilidae 610 $anervous system 610 $aneuroanatomy 610 $apaleontology 610 $aPantepui 610 $aphylogenomics 610 $aphylogeny 610 $areduced representation sequencing (RRS) 610 $arelict group 610 $aSalticidae 610 $aspeciation 610 $aspecies concepts 610 $aspecies turnover 610 $aspider phylogenomics 610 $aspiders 610 $atarget sequencing 610 $ataxonomic crisis 610 $ataxonomy 610 $aTetragnatha 610 $aTetragnathidae 610 $atissue 610 $atropical dry forests 610 $avicariance 610 $aX-rays 615 7$aBiology, life sciences 615 7$aMicrobiology (non-medical) 615 7$aResearch & information: general 702 $aKuntner$b Matjaz?$f1971- 906 $aBOOK 912 $a9910576872703321 996 $aPhylogenomic, Biogeographic, and Evolutionary Research Trends in Arachnology$93024200 997 $aUNINA LEADER 03180nam 2200421z- 450 001 9910220046703321 005 20210211 035 $a(CKB)3800000000216310 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/55353 035 $a(oapen)doab55353 035 $a(EXLCZ)993800000000216310 100 $a20202102d2016 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aOptogenetic Tools in the Molecular Spotlight 210 $cFrontiers Media SA$d2016 215 $a1 online resource (179 p.) 225 1 $aFrontiers Research Topics 311 08$a2-88919-899-5 330 $aThe rise of optogenetics as a standard technique to non-invasively probe and monitor biological function created an immense interest in the molecular function of photosensory proteins. These photoreceptors are usually protein/pigment complexes that translate light into biological information and have become essential tools in cell biology and neurobiology as their function is genetically encoded and can be conveniently delivered into a given cell. Like for fluorescent proteins that quickly became invaluable as genetically encodable reporters in microscopy and imaging, variants of photosensory proteins with customized sensitivity and functionality are nowadays in high demand. In this ebook we feature reviews and original research on molecular approaches from synthetic biology and molecular spectroscopy to computational molecular modelling that all aspire to elucidate the molecular prerequisites for the photosensory function of the given proteins. The principle property of changing activity of biological function simply by application of light is not only very attractive for cell biology, it also offers unique opportunities for molecular studies as excitation can be controlled with high time precision. Especially in spectroscopy the usually fully reversible photoactivation of photosensory proteins allows researchers to to perform time resolved studies with up to femtosecond resolution. In addition, functional variants can be investigated and quickly screened in common biochemical experiments. The insights that are obtained by the here presented various yet complementary methods will ultimately allow us write the script for a molecular movie from excitation of the protein by a photon to activation of its biological function. Such deep understanding does not only provide unique insights into the dynamics of protein function, it will also ultimately enable us to rationally design novel optogenetic tools to be used in cell biology and therapy. 610 $acomputational modeling 610 $aFlavins 610 $aOpsins 610 $aoptogenetics 610 $aPhotochemistry and photophysics 610 $aphotoreceptors 610 $aPhytochrome 610 $aProtein Engineering 610 $aspectroscopy 700 $aJohn T. M. Kennis$4auth$01320408 702 $aTilo Mathes$4auth 906 $aBOOK 912 $a9910220046703321 996 $aOptogenetic Tools in the Molecular Spotlight$93034272 997 $aUNINA