LEADER 02244nam  2200433z- 450 
001 9910220046503321
005 20231214133034.0
035   $a(CKB)3800000000216312
035   $a(oapen)https://directory.doabooks.org/handle/20.500.12854/51895
035   $a(EXLCZ)993800000000216312
100   $a20202102d2016      |y             0
101 0 $aeng
135   $aurmn|---annan
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aLiver Myofibroblasts
210   $cFrontiers Media SA$d2016
215   $a1 electronic resource (99 p.)
225 1 $aFrontiers Research Topics
311   $a2-88919-989-4 
330   $aMyofibroblasts (MFB) are found in most tissues of the body. They have the matrix-producing functions of fibroblasts and contractile properties that are known from smooth muscle cells. Fundamental work of the last decades has shed remarkable light on their origin, biological functions and role in disease. During hepatic injury, they fulfill manifold functions in connective tissue remodeling and wound healing, but overshooting activity of MFB on the other side induces fibrosis and cirrhosis. The present e-book "Liver myofibroblasts" contains 9 articles providing comprehensive information on "hot topics" of MFB. In our opening editorial we provide a short overview of the origin of MFB and their relevance in extracellular matrix formation which is the hallmark of hepatic fibrosis. Thereafter, leading experts in the field share their current perspectives on special topics of (i) MFB in development and disease, ii) their role in hepatic fibrogenesis, and (iii) promising therapies and targets that are suitable to interfere with hepatic fibrosis.
610   $aXanthohumol
610   $aHepatic Stellate Cells
610   $atherapy
610   $aPortal myofibroblasts
610   $aCytoglobin
610   $amiRNA
610   $aMyofibroblasts
610   $aAutophagy
610   $aMatrix stiffness
610   $aNADPH Oxidase
700   $aJiri Kanta$4auth$01315284
702   $aAlena Mrkvicova$4auth
702   $aRalf Weiskirchen$4auth
906   $aBOOK
912   $a9910220046503321
996   $aLiver Myofibroblasts$93032338
997   $aUNINA