LEADER 02316nam  2200457z- 450 
001 9910220045603321
005 20210211
035   $a(CKB)3800000000216321
035   $a(oapen)https://directory.doabooks.org/handle/20.500.12854/42362
035   $a(oapen)doab42362
035   $a(EXLCZ)993800000000216321
100   $a20202102d2017      |y         0
101 0 $aeng
135   $aurmn|---annan
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 00$aBone Marrow T Cells at the Center Stage in Immunological Memory
210   $cFrontiers Media SA$d2017
215   $a1 online resource (84 p.)
225 1 $aFrontiers Research Topics
311 08$a2-88945-093-7 
330   $aIncreasing evidence supports the notion that bone marrow (BM) represents a relevant player in T cell responses, particularly in its role as a specialized organ for long-term memory. Memory T cells are enriched in the BM over long times after priming, and can be recruited to the periphery upon antigenic challenge. The articles in this research topic include discussions of whether these T cells are passing-through or truly resident, as well as a debate on the extent of proliferation of BM memory T cells. Original research articles in this collection include an analysis of the number of memory T cells found in different bones as well as effects of B cell depletion on T cell memory in the BM. T cells in the BM can influence a number of processes, from bone remodeling, control of cancer, to effects on hemopoiesis or Graft versus Host Disease (GVHD). This research topic contains several contributions to these topics including discussions on how to translate BM T cell knowledge into medicine.
606   $aMedicine and Nursing$2bicssc
610   $aBone Marrow
610   $aCancer
610   $aCytokines
610   $agraft versus host disease
610   $aHomeostasis
610   $aHoming
610   $aMemory
610   $aniches
610   $aosteoimmunology
610   $aT cells
615  7$aMedicine and Nursing
700   $aFrancesca Di Rosa$4auth$01296293
702   $aTania H. Watts$4auth
906   $aBOOK
912   $a9910220045603321
996   $aBone Marrow T Cells at the Center Stage in Immunological Memory$93028024
997   $aUNINA