LEADER 01786nam2 2200385 i 450 001 SUN0070997 005 20130731013407.823 010 $a88-17-17017-8 100 $a20090723d1994 |0itac50 ba 101 $aita$aGRC 102 $aIT 105 $a|||| ||||| 200 1 $aˆ2: ‰Libri 4.-7.$fArriano 205 $aMilano : Rizzoli$b1994 210 $d322-685 p. ; 18 cm 215 $aSul frontespizio: Testo greco a fronte. 410 1$1001SUN0093936$12001 $aBUR. L$v1017$1210 $aMilano$cBUR. 461 1$1001SUN0070983$12001 $aAnabasi di Alessandro$fArriano$gtraduzione e note di Delfino Ambaglio$v2$1210 $aMilano$cRizzoli$d1994$1215 $a2 v.$d18 cm. 620 $dMilano$3SUNL000284 700 1$aArrianus$b, Flavius$3SUNV029161$04213 712 $aRizzoli$3SUNV000281$4650 790 0$aArrianus$zArrianus, Flavius$3SUNV029159 790 0$aFlavius Arrianus Nicomedensis$zArrianus, Flavius$3SUNV029160 790 0$aArriano$zArrianus, Flavius$3SUNV055902 790 0$aArrianus : Nicomediensis$zArrianus, Flavius$3SUNV058414 790 0$aArrien$zArrianus, Flavius$3SUNV058415 790 0$aArrianus, Flavius Lucius$zArrianus, Flavius$3SUNV091663 790 0$aFlavius Arrianus : Nicomedensis$zArrianus, Flavius$3SUNV091664 790 0$aArriano, Lucio Flavio$zArrianus, Flavius$3SUNV091665 801 $aIT$bSOL$c20190114$gRICA 912 $aSUN0070997 950 $aUFFICIO DI BIBLIOTECA DEL DIPARTIMENTO DI GIURISPRUDENZA$d00CONS XVIII.L.14 2 $e00 9624 20120524 950 $aUFFICIO DI BIBLIOTECA DEL DIPARTIMENTO DI LETTERE E BENI CULTURALI$d07CONS Xd 2 Arr $e07 79354 20090723 996 $aLibri 4.-7$91181755 997 $aUNICAMPANIA LEADER 05524nam 2200457z- 450 001 9910220045003321 005 20210211 035 $a(CKB)3800000000216327 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/53603 035 $a(oapen)doab53603 035 $a(EXLCZ)993800000000216327 100 $a20202102d2017 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aMitochondria in Skeletal Muscle Health, Aging and Diseases 210 $cFrontiers Media SA$d2017 215 $a1 online resource (142 p.) 225 1 $aFrontiers Research Topics 311 08$a2-88945-073-2 330 $aSkeletal muscle is the most abudant tissue of the human body, making up to 40 to 50% of the human body mass. While the importance of optimal muscle function is well recognized in the athletic field, its significance for general health is often underappreciated. In fact, the evidence that muscle mass, strength and metabolism are essential for our overall health is overwhelming. As the largest protein reservoir in the human body, muscles are essential in the acute response to critical illness such as sepsis, advanced cancer, and traumatic injury. Loss of skeletal muscle mass has also been associated with weakness, fatigue, insulin resistance, falls, fractures, frailty, disability, several chronic diseases and death. As a consequence, maintaining skeletal muscle mass, strength and metabolism throughout the lifespan is critical to the maintenance of whole body health. Mitochondria are fascinating organelles regulating many critical cellular processes for skeletal muscle physiology, including for instance energy supply, reactive oxygen species production, calcium homeostasis and the regulation of apoptosis. It is therefore not surprising that mitochondrial dysfunction has been implicated in a large number of adverse events/conditions and pathologies affecting skeletal muscle health. While the importance of normal mitochondrial function is well recognized for muscle physiology, there are important aspects of mitochondrial biology that are still poorly understood. These include mitochondrial dynamics (fusion and fission processes), morphology and processes involved in mitochondrial quality control (mitophagy). Defining the mechanisms regulating these different aspects of mitochondrial biology, their importance for muscle physiology, as well as the interrelations will be critical for expanding understanding of the role played by mitochondria in skeletal muscle physiology and health. The present research topic provides readers with novel experimental approaches, knowledge, hypotheses and findings related to all aspects of mitochondrial biology in healthy and diseased muscle cells.Skeletal muscle is the most abudant tissue of the human body, making up to 40 to 50% of the human body mass. While the importance of optimal muscle function is well recognized in the athletic field, its significance for general health is often underappreciated. In fact, the evidence that muscle mass, strength and metabolism are essential for our overall health is overwhelming. As the largest protein reservoir in the human body, muscles are essential in the acute response to critical illness such as sepsis, advanced cancer, and traumatic injury. Loss of skeletal muscle mass has also been associated with weakness, fatigue, insulin resistance, falls, fractures, frailty, disability, several chronic diseases and death. As a consequence, maintaining skeletal muscle mass, strength and metabolism throughout the lifespan is critical to the maintenance of whole body health. Mitochondria are fascinating organelles regulating many critical cellular processes for skeletal muscle physiology, including for instance energy supply, reactive oxygen species production, calcium homeostasis and the regulation of apoptosis. It is therefore not surprising that mitochondrial dysfunction has been implicated in a large number of adverse events/conditions and pathologies affecting skeletal muscle health. While the importance of normal mitochondrial function is well recognized for muscle physiology, there are important aspects of mitochondrial biology that are still poorly understood. These include mitochondrial dynamics (fusion and fission processes), morphology and processes involved in mitochondrial quality control (mitophagy). Defining the mechanisms regulating these different aspects of mitochondrial biology, their importance for muscle physiology, as well as the interrelations will be critical for expanding understanding of the role played by mitochondria in skeletal muscle physiology and health. The present research topic provides readers with novel experimental approaches, knowledge, hypotheses and findings related to all aspects of mitochondrial biology in healthy and diseased muscle cells. 606 $aPhysiology$2bicssc 610 $aAging 610 $aAtrophy 610 $aHypertrophy 610 $aMetabolism 610 $aMitochondria 610 $amitochondrial dynamics 610 $amitophagy 610 $amuscle contractility 610 $anutrition 610 $askeletal muscle 615 7$aPhysiology 700 $aGilles Gouspillou$4auth$01312905 702 $aRussell T. Hepple$4auth 906 $aBOOK 912 $a9910220045003321 996 $aMitochondria in Skeletal Muscle Health, Aging and Diseases$93031106 997 $aUNINA