LEADER 02407nam 2200409z- 450 001 9910220044803321 005 20210211 035 $a(CKB)3800000000216329 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/53838 035 $a(oapen)doab53838 035 $a(EXLCZ)993800000000216329 100 $a20202102d2016 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aMolecular Function and Regulation of Non-coding RNAs in Multifactorial Diseases 210 $cFrontiers Media SA$d2016 215 $a1 online resource (71 p.) 225 1 $aFrontiers Research Topics 311 08$a2-88945-002-3 330 $aOur understanding of the mechanisms underlying the development of multifactorial diseases such as diabetes, autism, Alzheimer's disease, and cancer has been greatly advanced. Non-coding RNAs (ncRNAs), generally including microRNAs and long non-coding RNAs, have recently been found to have potential roles in these diseases, and provide new opportunities for developing both specific biomarkers and therapeutic targets. However, the molecular function and regulation of these RNAs still remains challenging. Numerous studies are focusing on this field in order to fully appreciate the role and regulation of these molecules in human medicine and biology. This e-book aims to bring together new findings on Non-coding RNAs in different complex diseases. It will highlight the characterization, roles, mechanism, and mode of action of these RNAs in complex disorders. We believe that the publications on this topic would be exponentially extended in future. The improved approaches at multiple levels may pave the way for designing and applying new biomarker and therapeutic targets for specific diseases based on these attractive molecules. 606 $aGenetics (non-medical)$2bicssc 610 $abiomarker 610 $aCancer 610 $acomplex disease 610 $along non-coding RNA 610 $amiRNA 615 7$aGenetics (non-medical) 700 $aMohammadreza Hajjari$4auth$01317929 702 $aSeyed Javad Mowla$4auth 702 $aMohammad Ali Faghihi$4auth 906 $aBOOK 912 $a9910220044803321 996 $aMolecular Function and Regulation of Non-coding RNAs in Multifactorial Diseases$93033104 997 $aUNINA