LEADER 03694nam  2200445z- 450 
001 9910220042003321
005 20231214133408.0
035   $a(CKB)3800000000216357
035   $a(oapen)https://directory.doabooks.org/handle/20.500.12854/44741
035   $a(EXLCZ)993800000000216357
100   $a20202102d2016      |y             0
101 0 $aeng
135   $aurmn|---annan
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aDental and Periodontal Tissues Formation and Regeneration: Current Approaches and Future Challenges
210   $cFrontiers Media SA$d2016
215   $a1 electronic resource (246 p.)
225 1 $aFrontiers Research Topics
311   $a2-88919-984-3 
330   $aSequential and reciprocal interactions between oral epithelial and cranial neural crest-derived mesenchymal cells give rise to the teeth and periodontium. Teeth are vital organs containing a rich number of blood vessels and nerve fibers within the dental pulp and periodontium. Teeth are composed by unique and specific collagenous (dentin, fibrillar cementum) and non-collagenous (enamel) highly mineralized extracellular matrices. Alveolar bone is another collagenous hard tissue that supports tooth stability and function through its close interaction with the periodontal ligament. Dental hard tissues are often damaged after infection or traumatic injuries that lead to the partial or complete destruction of the functional dental and supportive tissues. Well-established protocols are routinely used in dental clinics for the restoration or replacement of the damaged tooth and alveolar bone areas. Recent progress in the fields of cell biology, tissue engineering, and nanotechnology offers promising opportunities to repair damaged or missing dental tissues. Indeed, pulp and periodontal tissue regeneration is progressing rapidly with the application of stem cells, biodegradable scaffolds, and growth factors. Furthermore, methods that enable partial dental hard tissue repair and regeneration are being evaluated with variable degrees of success. However, these cell-based therapies are still incipient and many issues need to be addressed before any clinical application. The understanding of tooth and periodontal tissues formation would be beneficial for improving regenerative attempts in dental clinics. In the present e-book we have covered the various aspects dealing with dental and periodontal tissues physiology and regeneration in 6 chapters: 1. General principles on the use of stem cells for regenerating craniofacial and dental tissues 2. The roles of nerves, vessels and stem cell niches in tissue regeneration 3. Dental pulp regeneration and mechanisms of various odontoblast functions 4. Dental root and periodontal physiology, pathology and regeneration 5. Physiology and regeneration of the bone using various scaffolds and stem cell populations 6. Physiology, pathology and regeneration of enamel using dental epithelial stem cells
517   $aDental and Periodontal Tissues Formation and Regeneration
610   $aStem Cells
610   $avasculature
610   $aRegenerative dentistry
610   $ascaffolds
610   $aPeriodontium
610   $aenamel
610   $aTooth
610   $ainnervation
610   $aDental Pulp
610   $aTissue Engineering
700   $aMitsiadis$b Thimios$4auth$01368116
702   $aOrsini$b Giovanna$4auth
702   $aArana Chavez$b Victor Elias$4auth
906   $aBOOK
912   $a9910220042003321
996   $aDental and Periodontal Tissues Formation and Regeneration: Current Approaches and Future Challenges$93392748
997   $aUNINA