LEADER 02256nam  2200361z- 450 
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035   $a(CKB)3800000000216372
035   $a(oapen)https://directory.doabooks.org/handle/20.500.12854/53852
035   $a(EXLCZ)993800000000216372
100   $a20202102d2016      |y             0
101 0 $aeng
135   $aurmn|---annan
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aMolecular Nanomachines of the Presynaptic Terminal
210   $cFrontiers Media SA$d2016
215   $a1 electronic resource (110 p.)
225 1 $aFrontiers Research Topics
311   $a2-88919-998-3 
330   $aSynaptic transmission is the basis of neuronal communication and is thus the most important element in brain functions, ranging from sensory input to information processing. Changes in synaptic transmission can result in the formation or dissolution of memories, and can equally lead to neurological and psychiatric disorders. The proteins composing the synapse, and their respective functions, are getting increasingly known. One aspect that has become evident in the last years is that most synaptic functions are performed not by single proteins, but by highly organized multi-protein machineries, which interact dynamically to provide responses optimally suited to the needs of the neuronal network. To decipher synaptic and neuronal function, it is essential to understand the organisational, morphological and functional aspects of the molecular nanomachines that operate at the synapse. We discuss these aspects in 11 different chapters, focusing on the structure and function of the active zone, on the functional anatomy of the synaptic vesicle, and on some of the best known soluble protein complexes from the synapse, including those involved in endocytosis and vesicle recycling.
610   $asynaptic protein
610   $aactive Zone
610   $ananomachine
610   $asynapse
610   $asynaptic vesicle
700   $aLucia Tabares$4auth$01353113
702   $aSilvio O. Rizzoli$4auth
906   $aBOOK
912   $a9910220040503321
996   $aMolecular Nanomachines of the Presynaptic Terminal$93220459
997   $aUNINA