LEADER 02116oam 2200481 450 001 9910706145803321 005 20170906103636.0 035 $a(CKB)5470000002454970 035 $a(OCoLC)1002927116 035 $a(OCoLC)995470000002454970 035 $a(EXLCZ)995470000002454970 100 $a20170906j200104 ua 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aMechanical properties of unirradiated and irradiated Zr-1% Nb cladding $eprocedures and results of low temperature biaxial burst tests and axial tensile tests /$fprepared by E. Kaplar [and ten others] 210 1$aWashington, DC :$cOffice of Nuclear Regulatory Research, U.S. Nuclear Regulatory Commission,$dApril 2001. 215 $a1 online resource (various pagings) $cillustrations 225 1 $aInternational agreement report ;$vNUREG/IA-0199 300 $a"IPSN 01-16." 300 $a"NSI RRC 2241." 300 $a"Nuclear Safety Institute of Russian Research Centre 'Kurchatov Institute.' " 300 $a"State Research Centre 'Research Institute of Atomic Reactors.' " 300 $a"April 2001." 300 $a"Prepared for U.S. Nuclear Regulatory Commission, Institute for Protection and Nuclear Safety (France), and Ministry of Science and Technologies (Russian Federation)." 320 $aIncludes bibliographical references. 517 $aMechanical properties of unirradiated and irradiated Zr-1% Nb cladding 606 $aNuclear fuel claddings$xTesting 606 $aZirconium alloys$xEffect of radiation on 606 $aNiobium alloys$xEffect of radiation on 615 0$aNuclear fuel claddings$xTesting. 615 0$aZirconium alloys$xEffect of radiation on. 615 0$aNiobium alloys$xEffect of radiation on. 700 $aKaplar$b E. P$g(Evgenii? Petrovich),$01389942 801 0$bGPO 801 1$bGPO 801 2$bGPO 906 $aBOOK 912 $a9910706145803321 996 $aMechanical properties of unirradiated and irradiated Zr-1% Nb cladding$93442110 997 $aUNINA LEADER 03066nam 2200469z- 450 001 9910220038403321 005 20210211 035 $a(CKB)3800000000216393 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/46422 035 $a(oapen)doab46422 035 $a(EXLCZ)993800000000216393 100 $a20202102d2016 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aEngineering Synthetic Metabolons: From Metabolic Modelling to Rational Design of Biosynthetic Devices 210 $cFrontiers Media SA$d2016 215 $a1 online resource (130 p.) 225 1 $aFrontiers Research Topics 311 08$a2-88919-921-5 330 $aThe discipline of Synthetic Biology has recently emerged at the interface of biology and engineering. The definition of Synthetic Biology has been dynamic over time ever since, which exemplifies that the field is rapidly moving and comprises a broad range of research areas. In the frame of this Research Topic, we focus on Synthetic Biology approaches that aim at rearranging biological parts/ entities in order to generate novel biochemical functions with inherent metabolic activity. This Research Topic encompasses Pathway Engineering in living systems as well as the in vitro assembly of biomolecules into nano- and microscale bioreactors. Both, the engineering of metabolic pathways in vivo, as well as the conceptualization of bioreactors in vitro, require rational design of assembled synthetic pathways and depend on careful selection of individual biological functions and their optimization. Mathematical modelling has proven to be a powerful tool in predicting metabolic flux in living and artificial systems, although modelling approaches have to cope with a limitation in experimentally verified, reliable input variables. This Research Topic puts special emphasis on the vital role of modelling approaches for Synthetic Biology, i.e. the predictive power of mathematical simulations for (i) the manipulation of existing pathways and (ii) the establishment of novel pathways in vivo as well as (iii) the translation of model predictions into the design of synthetic assemblies. 517 $aEngineering Synthetic Metabolons 606 $aHistory of engineering and technology$2bicssc 610 $aInteraction domains 610 $aMembrane Transport Proteins 610 $aMetabolic Engineering 610 $aMetabolic Modelling 610 $ametabolite profiling 610 $amolecular dynamics simulations 610 $aProtein Engineering 610 $aProtein scaffolds 610 $areconstitution 610 $aStarch biosynthesis 615 7$aHistory of engineering and technology 700 $aZoran Nikoloski$4auth$01303433 702 $aLars M. Voll$4auth 906 $aBOOK 912 $a9910220038403321 996 $aEngineering Synthetic Metabolons: From Metabolic Modelling to Rational Design of Biosynthetic Devices$93027037 997 $aUNINA