LEADER 04959nam 2200457z- 450 001 9910220037103321 005 20210211 035 $a(CKB)3800000000216406 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/50338 035 $a(oapen)doab50338 035 $a(EXLCZ)993800000000216406 100 $a20202102d2016 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aInsights into Microbe-Microbe Interactions in Human Microbial Ecosystems: Strategies to be Competitive 210 $cFrontiers Media SA$d2016 215 $a1 online resource (116 p.) 225 1 $aFrontiers Research Topics 311 08$a2-88945-052-X 330 $aAll parts of our body having communication with the external environment such as the skin, vagina, the respiratory tract or the gastrointestinal tract are colonized by a specific microbial community. The colon is by far the most densely populated organ in the human body. The pool of microbes inhabiting our body is known as "microbiota" and their collective genomes as "microbiome". These microbial ecosystems regulate important functions of the host, and their functionality and the balance among the diverse microbial populations is essential for the maintenance of a "healthy status". The impressive development in recent years of next generation sequencing (NGS) methods have made possible to determine the gut microbiome composition. This, together with the application of other high throughput omic techniques and the use of gnotobiotic animals has greatly improved our knowledge of the microbiota acting as a whole. In spite of this, most members of the human microbiota are largely unknown and remain still uncultured. The final functionality of the microbiota is depending not only on nutrient availability and environmental conditions, but also on the interrelationships that the microorganisms inhabiting the same ecological niche are able to establish with their partners, or with their potential competitors. Therefore, in such a competitive environment microorganisms have had to develop strategies allowing them to cope, adapt, or cooperate with their neighbors, which may imply notable changes at metabolic, physiological and genetic level. The main aim of this Research Topic was to contribute to better understanding complex interactions among microorganisms residing in human microbial habitats.All parts of our body having communication with the external environment such as the skin, vagina, the respiratory tract or the gastrointestinal tract are colonized by a specific microbial community. The colon is by far the most densely populated organ in the human body. The pool of microbes inhabiting our body is known as "microbiota" and their collective genomes as "microbiome". These microbial ecosystems regulate important functions of the host, and their functionality and the balance among the diverse microbial populations is essential for the maintenance of a "healthy status". The impressive development in recent years of next generation sequencing (NGS) methods have made possible to determine the gut microbiome composition. This, together with the application of other high throughput omic techniques and the use of gnotobiotic animals has greatly improved our knowledge of the microbiota acting as a whole. In spite of this, most members of the human microbiota are largely unknown and remain still uncultured. The final functionality of the microbiota is depending not only on nutrient availability and environmental conditions, but also on the interrelationships that the microorganisms inhabiting the same ecological niche are able to establish with their partners, or with their potential competitors. Therefore, in such a competitive environment microorganisms have had to develop strategies allowing them to cope, adapt, or cooperate with their neighbors, which may imply notable changes at metabolic, physiological and genetic level. The main aim of this Research Topic was to contribute to better understanding complex interactions among microorganisms residing in human microbial habitats. 517 $aInsights into Microbe-Microbe Interactions in Human Microbial Ecosystems 606 $aMicrobiology (non-medical)$2bicssc 610 $abacterial-pathogen infection 610 $aBacteroides 610 $aBifidobacterium 610 $aBiofilm 610 $abreast milk 610 $agnotobiotic mice 610 $ahuman microbiota 610 $aQuorum Sensing 610 $aShort Chain Fatty Acids 615 7$aMicrobiology (non-medical) 700 $aClara G. de los Reyes-Gavilan$4auth$01305923 702 $aNuria Salazar$4auth 906 $aBOOK 912 $a9910220037103321 996 $aInsights into Microbe-Microbe Interactions in Human Microbial Ecosystems: Strategies to be Competitive$93028022 997 $aUNINA