LEADER 04069nam 2200697 450 001 9910819596403321 005 20200903223051.0 010 $a90-04-26673-9 024 7 $a10.1163/9789004266735 035 $a(CKB)2670000000578882 035 $a(EBL)1877187 035 $a(SSID)ssj0001343746 035 $a(PQKBManifestationID)12602208 035 $a(PQKBTitleCode)TC0001343746 035 $a(PQKBWorkID)11310601 035 $a(PQKB)11658622 035 $a(MiAaPQ)EBC1877187 035 $a(nllekb)BRILL9789004266735 035 $a(Au-PeEL)EBL1877187 035 $a(CaPaEBR)ebr10992556 035 $a(CaONFJC)MIL666145 035 $a(OCoLC)897378898 035 $a(PPN)184932009 035 $a(EXLCZ)992670000000578882 100 $a20141220h20152015 uy 0 101 0 $aeng 135 $aurun| uuuua 181 $ctxt 182 $cc 183 $acr 200 14$aThe semantics of free indirect discourse $ehow texts allow us to mind-read and eavesdrop /$fby Regine Eckardt 210 1$aLeiden, Netherlands :$cBRILL,$d2015. 210 4$dİ2015 215 $a1 online resource (295 p.) 225 1 $aCurrent Research in the Semantics/Pragmatics Interface,$x1472-7870 ;$vVolume 31 300 $aDescription based upon print version of record. 311 $a1-322-34863-4 311 $a90-04-26672-0 320 $aIncludes bibliographical references and index. 327 $aFront Matter -- Introduction -- The Contexts of Free Indirect Discourse -- Story Update -- Tense and Aspect -- Particles in Free Indirect Discourse -- Exclamatives -- Predecessors and Alternatives -- More Tenses, More Moods -- Forbidden in Shifted Speech -- Final Panorama -- A Summary of Formal Proposals -- References -- Index. 330 $aFree indirect discourse presents us with the inner world of protagonists of a story. We seem to see the world through their eyes, and listen to their inner thoughts. The present study analyses the logic of free indirect discourse and offers a framework to represent multiple ways in which words betray the speaker's feelings and attitude. The theory covers tense, aspect, temporal indexicals, modal particles, exclamatives and other expressive elements and their dependence on shifting utterance contexts. It traces the subtle ways in which story texts can offer information about protagonists. The study of free indirect discourse has been a topic of great interest in recent years in semantics and pragmatics. In this book, Regine Eckardt proposes a new theory of this domain and applies it to a wide variety of phenomena -- discourse particles, exclamatives, and mood -- in addition to the traditional indexical pronouns and tenses. She situates this project within a larger attempt to extend the tools of semantic analysis to fiction. Most formally oriented semanticists have not paid serious attention to this domain, which has resulted in a major gap in semantic theory; this book is thus a pioneering effort and raises many intriguing points. The total result is an empirically rich and exciting work which will be a profitable read for researchers interested in semantics, pragmatics, and formal approaches to literature. Eric McCready, Aoyama Gakuin University 410 0$aCurrent research in the semantics/pragmatics interface ;$vVolume 31. 606 $aGrammar, Comparative and general$xIndirect discourse 606 $aSemantics, Comparative 606 $aGrammar, Comparative and general$xVerb phrase 606 $aCognitive grammar 606 $aPsycholinguistics 615 0$aGrammar, Comparative and general$xIndirect discourse. 615 0$aSemantics, Comparative. 615 0$aGrammar, Comparative and general$xVerb phrase. 615 0$aCognitive grammar. 615 0$aPsycholinguistics. 676 $a401/.43 700 $aEckardt$b Regine$01095357 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910819596403321 996 $aThe semantics of free indirect discourse$94061481 997 $aUNINA LEADER 03525nam 2200457z- 450 001 9910220036903321 005 20210212 035 $a(CKB)3800000000216408 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/61392 035 $a(oapen)doab61392 035 $a(EXLCZ)993800000000216408 100 $a20202102d2017 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aTumor Hypoxia: Impact in Tumorigenesis, Diagnosis, Prognosis and Therapeutics 210 $cFrontiers Media SA$d2017 215 $a1 online resource (113 p.) 225 1 $aFrontiers Research Topics 311 08$a2-88945-064-3 330 $aHypoxic regions have been identified within tumors and its presence has been linked to malignant progression, metastasis, resistance to therapy, and poor clinical outcomes following treatment. Acute and chronic hypoxia are integral components of tumor microenvironment and conduce to metabolic adaptations of tumor cells leading to genetic instability, intratumor heterogeneity and malignant progression. On the success of our fight against cancer, the continued adaptability of tumors to their microenvironmental stresses, such as hypoxia, must be considered. Tumor cells are endowed with a very high plasticity and capacity to adapt. It is our challenge to find populations and conditions of the tumor microenvironment germane for target success. Interdisciplinary work will be the key for achievement of these goals. This e-book is a compendium of original reports and review articles contributed by world-class experts in the field of tumor hypoxia. This material will be useful to foster discussion and increase understanding of the involvement of hypoxia in tumorigenesis, biomarker development, and therapeutics.Hypoxic regions have been identified within tumors and its presence has been linked to malignant progression, metastasis, resistance to therapy, and poor clinical outcomes following treatment. Acute and chronic hypoxia are integral components of tumor microenvironment and conduce to metabolic adaptations of tumor cells leading to genetic instability, intratumor heterogeneity and malignant progression. On the success of our fight against cancer, the continued adaptability of tumors to their microenvironmental stresses, such as hypoxia, must be considered. Tumor cells are endowed with a very high plasticity and capacity to adapt. It is our challenge to find populations and conditions of the tumor microenvironment germane for target success. Interdisciplinary work will be the key for achievement of these goals. This e-book is a compendium of original reports and review articles contributed by world-class experts in the field of tumor hypoxia. This material will be useful to foster discussion and increase understanding of the involvement of hypoxia in tumorigenesis, biomarker development, and therapeutics. 517 $aTumor Hypoxia 606 $aMedicine$2bicssc 610 $abiomarkers 610 $aHIF 610 $ahypoxia 610 $aLeukemia 610 $amicroenvironment 610 $apH 610 $aStem Cells 610 $astress 610 $atherapy 610 $atumor 615 7$aMedicine 700 $aChristian R. Gomez$4auth$01296299 906 $aBOOK 912 $a9910220036903321 996 $aTumor Hypoxia: Impact in Tumorigenesis, Diagnosis, Prognosis and Therapeutics$93023973 997 $aUNINA