LEADER 03267nam  2200373z- 450 
001 9910220036703321
005 20231214133259.0
035   $a(CKB)3800000000216410
035   $a(oapen)https://directory.doabooks.org/handle/20.500.12854/42083
035   $a(EXLCZ)993800000000216410
100   $a20202102d2017      |y             0
101 0 $aeng
135   $aurmn|---annan
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aBifidobacteria and Their Role in the Human Gut Microbiota
210   $cFrontiers Media SA$d2017
215   $a1 electronic resource (242 p.)
225 1 $aFrontiers Research Topics
311   $a2-88945-100-3 
330   $aThe human intestine is home of an almost inconceivable large number of microorganisms. The human gut microbiota can therefore be pictured as an organ placed within a host organism. The human gut microbiome, which in total may contain >100 times the number of genes present in our genome, endows us with functional features that we did not have to evolve ourselves. It is recognized that intestinal microbiota plays an important role in human health and disease. In fact, gut bacteria other than metabolize dietary components, may play complex roles such as modulation of the immune system and in reduction of gut infections. Variations in the presence and/or abundance of certain components of the intestinal microbiota have repeatedly been observed in patients that suffer from atopic diseases, inflammatory bowel disease, Crohn disease, ulcerative colitis, infectious colitis, colon cancer and diabetes. In this context, bifidobacteria represent one of the most common bacterial members of the human gut microbiota. Bifidobacteria are anaerobic, Gram-positive, irregular or branched rod-shaped bacteria that are commonly found in the gastro-intestinal tracts (GIT) of humans, especially during the first stages of life and most animal and insects. Bifidobacterial fluctuations seem directly associated with health effects and for these reasons they are being exploited as health-promoting or probiotic bacteria. However, despite the extensive commercial exploitation of bifidobacteria as probiotic bacteria, little is known about their impact or dependency on other members of the human gut microbiota or on their host. Genome analyses have highlighted the existence of gene repertoires encoding products that are responsible for the adaptation of bifidobacteria to the human intestine and intense research efforts at international level are ongoing to understand the molecular details of these interactions. Specifically, the molecular interactions that are presumed to exist between bifidobacteria and the human host, as well as interactions between different residents of intestinal microbiota are the main topic of bifidobacterial research communities.
610   $abifidobacteria
610   $aGenomics
610   $aGut Microbiota
610   $aEcology
610   $aProbiogenomics
700   $aFrancesca Turroni$4auth$01328966
702   $aMarco Ventura$4auth
702   $aDavid Berry$4auth
906   $aBOOK
912   $a9910220036703321
996   $aBifidobacteria and Their Role in the Human Gut Microbiota$93040698
997   $aUNINA