LEADER 01939nam 2200469z- 450 001 9910220035503321 005 20210212 035 $a(CKB)3800000000216422 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/60746 035 $a(oapen)doab60746 035 $a(EXLCZ)993800000000216422 100 $a20202102d2017 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aTertiary Lymphoid Organs (TLOs): Powerhouses of Disease Immunity 210 $cFrontiers Media SA$d2017 215 $a1 online resource (235 p.) 225 1 $aFrontiers Research Topics 311 08$a2-88945-180-1 330 $aThe immune system employs TLOs to elicit highly localized and forceful responses to unresolvable peripheral tissue inflammation. Current data indicate that TLOs are protective but they may also lead to collateral tissue injury and serve as nesting places to generate autoreactive lymphocytes. A better comprehension of these powerhouses of disease immunity will likely facilitate development to unprecedented and specific therapies to fight chronic inflammatory diseases. 517 $aTertiary Lymphoid Organs 606 $aMedicine and Nursing$2bicssc 610 $aantigen 610 $aAutoimmunity 610 $aAutoinflammation 610 $adichotomies of immune responses 610 $adisease immunity 610 $aImmune Tolerance 610 $anonresolving peripheral tissue inflammation 610 $aTertiary lymphoid organs 615 7$aMedicine and Nursing 700 $aChangjun Yin$4auth$01278176 702 $aAndreas J.R. Habenicht$4auth 702 $aPasquale Maffia$4auth 702 $aSarajo Mohanta$4auth 906 $aBOOK 912 $a9910220035503321 996 $aTertiary Lymphoid Organs (TLOs): Powerhouses of Disease Immunity$93012763 997 $aUNINA