LEADER 05545oam 2200481I 450 001 9910163881903321 005 20230810002110.0 010 $a1-315-27817-0 010 $a1-315-27815-4 010 $a1-315-27816-2 024 7 $a10.1201/b21922 035 $a(CKB)3710000001051154 035 $a(MiAaPQ)EBC4799803 035 $a(OCoLC)971586286 035 $a(EXLCZ)993710000001051154 100 $a20180417d2017 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $2rdacontent 182 $2rdamedia 183 $2rdacarrier 200 00$aImaging in photodynamic therapy /$fedited by Michael R. Hamblin, Yingying Huang 205 $aFirst edition. 210 1$aBoca Raton, FL :$cRoutledge, an imprint of Taylor and Francis,$d2017. 215 $a1 online resource (502 pages) $ccolor illustrations, tables 225 1 $aSeries in Cellular and Clinical Imaging 311 $a1-4987-4145-2 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $tpart PART 1INTRODUCTION -- $tchapter 1 Looking out the optical window: Physical principles and instrumentation of imaging in?photodynamic therapy /$rHui Liu -- $tchapter 2 Photochemistry and photophysics of PDT and?photosensitizers /$rMarcin Ptaszek -- $tpart PART 2 IN VITRO MICROSCOPY FOR PHOTOSENSITIZER LOCALIZATION IN CELLS -- $tchapter 3 Phthalocyanines in photodynamic therapy /$rHeidi Abrahamse -- $tchapter 4 Singlet oxygen luminescence imaging: A prospective tool in bioscience? /$rMichael Pfitzner, Jan C. Schlothauer, Lisheng Lin, Buhong?Li, and Beate R?der -- $tchapter 5 Microbial biofilms and antimicrobial photodynamic therapy /$rAnil Kishen -- $tchapter 6 High-content imaging for photosensitizer screening /$rGisela M.F. Vaz, Mathias O. Senge, Sarah-Louise Ryan, and?Anthony Davies -- $tpart PART 3: IN VITRO MICROSCOPY OF CELL DAMAGE AND DEATH PROCESSES AFTER?PDT -- $tchapter 7 Enhanced efficacy of photodynamic therapy via an iron?lysosome?mitochondria connection: Studies with phthalocyanine 4 /$rAnna-Liisa Nieminen, Hsin-I Hung, and John J. Lemasters -- $tchapter 8 Role of cell death pathways in response to photodynamic therapy in gliomas /$rLeonardo Barcelos de Paula, Fernando Lucas Primo, and?Antonio Claudio Tedesco -- $tchapter 9 In search of specific PDT photosensitizers: Subcellular localization and cell death pathways /$rTayana M. Tsubone, Christiane Pavani, Isabel O.L. Bacellar, and Maur?cio S. Baptista -- $tpart PART 4 THERANOSTIC AGENTS AND NANOTECHNOLOGY -- $tchapter 10 Quantum dots in PDT -- $tchapter 11 Tetrapyrrole-based theranostic combinations of photodynamic action and magnetic resonance imaging /$rDuygu Aydin Tekdas, Devrim Atilla, Vefa Ahsen, and Ays?e G?l G?rek -- $tchapter 12 Theranostic applications of photodynamic molecular beacons /$rWentao Song -- $tchapter 13 Tumor-specific imaging and photodynamic therapy targeting the urokinase receptor /$rZafar Iqbal, Longguang Jiang, Zhuo Chen, Cai Yuan, Rui Li, Ke Zheng, Xiaolei Zhou, Jincan Chen, Ping Hu, and?Mingdong Huang -- $tpart PART 5 SMALL ANIMAL IMAGING -- $tchapter 14 Vascular imaging in photodynamic therapy /$rBin Chen -- $tchapter 15 Photosensitizer activity imaging on the microscopic scale /$rSteffen Hackbarth -- $tchapter 16 Bioluminescence imaging for monitoring the effectiveness of photodynamic therapy for infections in animal models /$rPawel Mroz -- $tpart PART 6 CLINICAL IMAGING -- $tchapter 17 Imaging of photosensitizers in skin /$rMarica B. Ericson -- $tchapter 18 Brain tumor imaging with ALA /$rHerbert Stepp -- $tchapter 19 PDT of non-muscle-invasive bladder cancer with Hexylester Aminolevulinate: Optimization of the illumination wavelengths by fluorescence spectroscopy and imaging /$rMatthieu Zellweger -- $tchapter 20 Endoscopic imaging and photodynamic therapy /$rHarubumi Kato, Kinya Furukawa, Yasufumi Kato, Jitsuo Usuda, Kuniharu Miyajima, and?Keishi Ohtani -- $tchapter 21 Spectroscopic imaging in prostate PDT /$rRozhin Penjweini -- $tchapter 22 Fluorescent-guided resection in clinical oncology /$rRon R. Allison. 330 3 $aThis book covers the broad field of cellular, molecular, preclinical, and clinical imaging either associated with or combined with photodynamic therapy (PDT). It showcases how this approach is used clinically for cancer, infections, and diseases characterized by unwanted tissue such as atherosclerosis or blindness. Because the photosensitizers are also fluorescent, the book also addresses various imaging systems such as confocal microscopy and small animal imaging systems, and highlights how they have been used to follow and optimize treatment, and to answer important mechanistic questions. Chapters also discuss how imaging has made important contributions to clinical outcomes in skin, bladder, and brain cancers, as well as in the development of theranostic agents for detection and treatment of disease. This book provides a resource for physicians and research scientists in cell biology, microscopy, optics, molecular imaging, oncology, and drug discovery. 410 0$aSeries in cellular and clinical imaging. 606 $aPhotochemotherapy 615 0$aPhotochemotherapy. 676 $a615.831 700 $aHamblin$b Michael R.$01166061 702 $aHamblin$b Michael R. 702 $aHuang$b Ying-Ying 801 0$bFlBoTFG 801 1$bFlBoTFG 906 $aBOOK 912 $a9910163881903321 996 $aImaging in photodynamic therapy$92890058 997 $aUNINA