LEADER 05929nam 2200697Ia 450 001 9910163021503321 005 20170821170455.0 010 $a1-283-15369-6 010 $a9786613153692 010 $a3-8055-9451-8 035 $a(CKB)2610000000006644 035 $a(EBL)3016412 035 $a(SSID)ssj0000542911 035 $a(PQKBManifestationID)12250595 035 $a(PQKBTitleCode)TC0000542911 035 $a(PQKBWorkID)10511721 035 $a(PQKB)11391043 035 $a(MiAaPQ)EBC3016412 035 $a(OCoLC)655260511 035 $a(SZ-BaSKA)253872 035 $a(PPN)156478013 035 $a(EXLCZ)992610000000006644 100 $a20100310d2010 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aAdipose tissue development$b[electronic resource] $efrom animal models to clinical conditions : 3rd ESPE Advanced Seminar in Developmental Endocrinology, Paris, March 12-13, 2009 /$fvolume editors, Claire Levy-Marchal, Luc Pe?nicaud 210 $aBasel ;$aNew York $cKarger$dc2010 215 $a1 online resource (105 p.) 225 0 $aEndocrine development,$x1421-7082 ;$vv. 19 300 $aDescription based upon print version of record. 311 $a3-8055-9450-X 320 $aIncludes bibliographical references and indexes. 327 $a""Cover""; ""Contents""; ""Preface""; ""Human Lipodystrophies: Genetic and Acquired Diseases of Adipose Tissue""; ""Abstract""; ""Definition and Diagnosis""; ""Classification""; ""Pathophysiology of Adipose Tissue Loss""; ""Genetic Lipodystrophies""; ""Acquired Lipodystrophies""; ""Treatment of Lipodystrophies""; ""Conclusion""; ""Acknowledgements""; ""References""; ""The Emergence of Adipocytes""; ""Abstract""; ""The Adipose Organ""; ""Developmental Origin of Fat""; ""Origin of Adipocytes""; ""Conclusion""; ""References""; ""Adipose Tissue and the Reproductive Axis: Biological Aspects"" 327 $a""Abstract""""Adipose Tissue as an Endocrine Organ""; ""Gene Expression in Subcutaneous Adipose Tissue from Growing Pigs and Neonatal and Fetal Pigs""; ""Adipose Depot Innervation""; ""Adipokines and Reproductive Function""; ""References""; ""Unraveling the Obesity and Breast Cancer Links: A Role for Cancer-Associated Adipocytes?""; ""Abstract""; ""Adipose Tissue Is an Active Component of the Tumor Stroma""; ""Consequences for the Poor Prognosis Observed for Breast Cancer in Obese Patients: Some Answers, Many Questions""; ""Acknowledgements""; ""References""; ""Early Determinants of Obesity"" 327 $a""Abstract""""Infancy Is a Risk Period for Later Obesity""; ""Infancy Weight and Subsequent Puberty""; ""Common Genetic Determinants of Childhood Obesity""; ""Life-Course Associations with FTO and MC4R Variants""; ""Nutritional Regulation of Infancy Growth""; ""Biomarkers of Infant Growth and Adiposity""; ""Influence of Maternal Glucose on Birth Size and Infancy Growth""; ""Wider Determinants of Infant Feeding and Weight Gain""; ""Determinants of Parental Feeding Choices""; ""References""; ""Metabolic Syndrome in Childhood a??? Causes and Effects""; ""Abstract"" 327 $a""Pathophysiology of the Insulin Resistance Syndrome in Childhood""""The Complexity of Definitions of the Metabolic Syndrome""; ""Clinical Relevance""; ""Conclusion""; ""References""; ""Pathophysiology of Insulin Resistance in Small for Gestational Age Subjects: A Role for Adipose Tissue?""; ""Abstract""; ""Epidemiological Data""; ""Low Birth Weight and Insulin Resistance""; ""Insulin Resistance in Subjects Born SGA Can Be Detected Early in Life""; ""Postnatal Growth""; ""Pathway to Insulin Resistance""; ""Role of Adipose Tissue"" 327 $a""Reduced Fetal Growth and Hormonal Function of the Adipose Tissue""""Fat Growth and Insulin Resistance""; ""Conclusion""; ""References""; ""The Neural Feedback Loop between the Brain and Adipose Tissues""; ""Abstract""; ""From the Brain to Adipose Tissues""; ""Role of Autonomic Nervous System in Adipose Tissues Biology""; ""From the Adipose Tissues to the Brain""; ""Perspectives""; ""References""; ""Author Index""; ""Subject Index"" 330 $aNowadays, adipose tissue is not only regarded as an organ of storage related to fuel metabolism but also as an endocrine organ involved in the regulation of insulin sensitivity, lipids and energy metabolism. These proceedings cover the nervous regulation of both white and brown adipose tissue mass. Different physiological parameters such as metabolism (lipolysis and thermogenesis) and secretory activity (leptin and other adipokines) are reviewed. The plasticity of adipose tissue (proliferation, differentiation and apoptosis) showing the presence of a neural feedback loop between adipose tissue and the brain, which plays a major role in the regulation of energy homeostasis, is discussed. Merging basic knowledge and various clinical conditions, this thorough review is of great interest to both scientists and physicians, in particular pediatricians, interested in obesity, endocrinology and nutrition. 410 0$aEndocrine Development 606 $aAdipose tissues$xPathophysiology$vCongresses 606 $aAdipose tissues$xDiseases$xEndocrine aspects$vCongresses 606 $aMetabolic syndrome$vCongresses 606 $aDevelopmental endocrinology$vCongresses 615 0$aAdipose tissues$xPathophysiology 615 0$aAdipose tissues$xDiseases$xEndocrine aspects 615 0$aMetabolic syndrome 615 0$aDevelopmental endocrinology 676 $a571.5/7 701 $aLevy-Marchal$b C$g(Claire)$01208782 701 $aPe?nicaud$b Luc$01208783 712 12$aESPE Advanced Seminar in Developmental Endocrinology 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910163021503321 996 $aAdipose tissue development$92788931 997 $aUNINA