LEADER 05814nam 2200625 450 001 9910163020403321 005 20170816162532.0 010 $a3-318-02527-5 035 $a(CKB)3710000000094773 035 $a(EBL)3016610 035 $a(SSID)ssj0001173062 035 $a(PQKBManifestationID)11977418 035 $a(PQKBTitleCode)TC0001173062 035 $a(PQKBWorkID)11194747 035 $a(PQKB)10534438 035 $a(MiAaPQ)EBC3016610 035 $a(OCoLC)878671093 035 $a(SZ-BaSKA)261300 035 $a(PPN)195785762 035 $a(EXLCZ)993710000000094773 100 $a20140407h20142014 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aHuman papillomavirus $ebench to bedside /$fvolume editors, Marigdalia K. Rami?rez-Fort [and three others] 210 1$aBasel, Switzerland :$cKarger,$d2014. 210 4$dİ2014 215 $a1 online resource (282 p.) 225 1 $aCurrent Problems in Dermatology,$x1421-5721 ;$vVolume 45 300 $aDescription based upon print version of record. 311 $a3-318-02526-7 320 $aIncludes bibliographical references at the end of each chapters and indexes. 327 $a""Cover""; ""Front Matter""; ""Contents""; ""Foreword""; ""Introduction""; ""Human Papillomavirus Genomics: Past, Present and Future""; ""Abstract""; ""Human Papillomavirus Genome Characteristics""; ""Viral Identification and Classification: Phylogeny and Taxonomy""; ""Human Papillomavirus Classification""; ""Human Papillomavirus Genome a???Typinga???""; ""Variant Lineages: Model for Recent Human Papillomavirus Speciation""; ""The Future of Human Papillomavirus Genomics""; ""References""; ""Molecular Biology and Pathogenesis""; ""The Biology of Human Papillomaviruses""; ""Abstract"" 327 $a""Introduction""""Virion and Genome Structure""; ""Human Papillomavirus Types""; ""Viral Life Cycle""; ""Genome Integration and Expression""; ""Clearance, Latency and Asymptomatic Infection""; ""Conclusion""; ""References""; ""Viral Oncogenesis""; ""Abstract""; ""Mechanisms of Viral Oncogenesis""; ""Conclusion""; ""References""; ""Pathogenesis of Infection by Human Papillomavirus""; ""Abstract""; ""Human Papillomavirus Disease Associations""; ""Human Papillomavirus Variants and Pathogenesis""; ""Human Papillomavirus Infection and Life Cycle"" 327 $a""Risk Factors Associated with Human Papillomavirus Pathogenesis""""Conclusion""; ""References""; ""Host Responses to Infection with Human Papillomavirus""; ""Abstract""; ""Human Papillomavirus Infection and Immune Deficiency""; ""Severe Combined Immune Deficiency""; ""DOCK8 Mutations and SCID""; ""MonoMAC Syndrome and GATA2 Deficiency""; ""Common Variable Immune Deficiency""; ""Epidermodysplasia Verruciformis""; ""WHIM Syndrome""; ""WILD and Emberger Syndrome""; ""Primary Intestinal Lymphangiectasia""; ""Idiopathic CD4 Lymphocytopenia""; ""Fanconi Anaemia""; ""Organ Transplant Recipients"" 327 $a""HIV Infection""""Human Papillomavirus Is a Successful Pathogen""; ""Human Papillomavirus Immune Evasion Strategies""; ""High-Risk Human Papillomaviruses Downregulate Interferon Responses""; ""Human Papillomavirus Globally Downregulates Keratinocyte Cytokine Responses in Episome-Containing Keratinocytes""; ""The Immune Response to Human Papillomavirus in Natural Infections""; ""Humoral Response to Human Papillomavirus Infection""; ""References""; ""Epidemiology and Clinical Manifestations""; ""The Epidemiology of Human Papillomaviruses""; ""Abstract""; ""Epidemiology"" 327 $a""Genital Infection and Associated Factors""""Anal Infection and Associated Factors""; ""Oral Infection and Associated Factors""; ""Cutaneous Infection and Associated Factors""; ""Serological Responses to HPV""; ""Epidemiology of Human Papillomavirus-Associated Disease""; ""Genital Warts""; ""Cancer""; ""Cutaneous Disease""; ""Conclusion""; ""References""; ""Cutaneous Human Papillomavirus Infection: Manifestations and Diagnosis""; ""Abstract""; ""Clinical Forms""; ""Dermatoscopy""; ""References""; ""Genitoanal Human Papillomavirus Infection and Associated Neoplasias""; ""Abstract"" 327 $a""Genitoanal Warts in Adults"" 330 $aHuman papillomavirus (HPV) infection transcends multiple fields of science and medicine. The management of HPV-related disease is demanding and often requires a persistent multimodal approach involving various medical disciplines. In this volume, experts present a comprehensive view of HPV research with an emphasis on clinical presentations, diagnosis, management and vaccine development. The state of the art in molecular biology is provided in addition to discussions on clinical morphology and the utility of dermatoscopy in identifying HPV disease. In a multidisciplinary approach to dermatological, plastic and reconstructive, gynecological, otolaryngological and colorectal management, different treatment strategies are highlighted. Finally, Dr. Neil Christensen discusses viral immunology, and the difficulties and successes in the development of an HPV vaccine. Bringing together basic science and clinical information on HPV, this book is an excellent resource and reference for all researchers and clinicians who encounter human papillomavirus-related disease. 410 0$aCurrent problems in dermatology ;$vVolume 45. 606 $aPapillomavirus diseases 606 $aPapillomaviruses 615 0$aPapillomavirus diseases. 615 0$aPapillomaviruses. 676 $a616.911 702 $aRami?rez-Fort$b Marigdalia K. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910163020403321 996 $aHuman Papillomavirus$92176951 997 $aUNINA