LEADER 04618nam 2200601 450 001 9910163020303321 005 20170817193453.0 010 $a3-318-02585-2 035 $a(CKB)3710000000110018 035 $a(EBL)3016616 035 $a(SSID)ssj0001255985 035 $a(PQKBManifestationID)11977958 035 $a(PQKBTitleCode)TC0001255985 035 $a(PQKBWorkID)11258984 035 $a(PQKB)11213558 035 $a(MiAaPQ)EBC3016616 035 $a(OCoLC)880140569 035 $a(SZ-BaSKA)261409 035 $a(PPN)195795083 035 $a(EXLCZ)993710000000110018 100 $a20140508h20142014 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aCell-based therapy for retinal degenerative disease /$fvolume editors, Ricardo P. Casaroli-Marano, Marco A. Zarbin ; Petr Baranov [and forty three others], contributors 210 1$aBasel, Switzerland :$cKarger,$d2014. 210 4$dİ2014 215 $a1 online resource (220 p.) 225 1 $aDevelopments in Ophthalmology,$x1662-2790 ;$vVolume 53 300 $aDescription based upon print version of record. 311 $a1-306-69557-0 311 $a3-318-02584-4 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aAge-related macular degeneration: clinical findings, histopathology, and imaging techniques / Zarbin, M.A.; Casaroli-Marano, R.; Rosenfeld, P.J. -- General pathophysiology in retinal degeneration / Wert, K.J.; Lin, J.H.; Tsang, S.H. -- Juvenile-onset macular degeneration and allied disorders / North, V.; Gelman, R.; Tsang, S.H. -- Diagnosis and complementary examinations / Menghini, M.; Duncan, J.L. -- Stem cells for retinal repair / Stern, J.; Temple, S. -- Differentiation of pluripotent stem cells into retinal pigmented epithelium / Croze, R.H.; Clegg, D.O. -- Neural retinal regeneration with pluripotent stem cells / Ramsden, C.M.; Powner, M.B.; Carr, A.-J.F.; Smart, M.J.K.; da Cruz, L.; Coffey, P.J. -- Stem cells, retinal ganglion cells and glaucoma / Sluch, V.M.; Zack, D.J. -- Stem cells : immunology and immunomodulation / Tena, A.; Sachs, D.H. -- Biochemical restoration of aged human Bruch's membrane : experimental studies to improve retinal pigment epithelium transplant survival and differentiation / Sugino, I.K.; Sun, Q.; Cheewatrakoolpong, N.; Malcuit, C.; Zarbin, M.A. -- Approaches to cell delivery : substrates and scaffolds for cell therapy / Kundu, J.; Michaelson, A.; Baranov, P.; Young, M.J.; Carrier, R.L. -- Microdevice-based cell therapy for age-related macular degeneration / Lu, B.; Tai, Y.-C.; Humayun, M.S. -- Cell and gene therapy / Rao, R.C.; Zacks, D.N. -- Cellular manufacturing for clinical applications / Sheu, J.; Klassen, H.; Bauer, G. -- Regulatory issues in cell-based therapy for clinical purposes / Casaroli-Marano, R.P.; Tabera, J.; Vilarrodona, A.; Trias, E. 330 $aIn this volume, some of the leading authorities present their exploration of applications of stem cell therapy to the treatment of major causes of blindness, including degenerative diseases and glaucoma. The diagnostic approach to patients, general concepts of cell-based therapy, immunological considerations, approaches to cell delivery (including engineered scaffolds), combined cell and gene therapy, nanomedicine applications to cell therapy and regulatory issues pertaining to manufacture and production are all considered in detail. The book serves as an excellent introduction to a field that is now entering early-stage clinical trials and promises to operate at the leading edge of regenerative medicine. Retina specialists, general ophthalmologists as well as researchers will find here a wealth of information on the translational aspects of cell-based therapies. Further, business executives and students interested in understanding the potential applications of stem cell therapy to retinal degenerative disease and glaucoma will also find this book informative reading. 410 0$aDevelopments in ophthalmology ;$vVolume 53. 606 $aRetinal degeneration 606 $aStem cells$xTransplantation 615 0$aRetinal degeneration. 615 0$aStem cells$xTransplantation. 676 $a617.7/35 702 $aCasaroli-Marano$b Ricardo Pedro 702 $aZarbin$b Marco A. 702 $aBaranov$b Pe??tr 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910163020303321 996 $aCell-based therapy for retinal degenerative disease$92788818 997 $aUNINA