LEADER 03633nam 22005775 450 001 9910163014603321 005 20200701162737.0 010 $a3-319-48927-5 024 7 $a10.1007/978-3-319-48927-8 035 $a(CKB)3710000001006641 035 $a(DE-He213)978-3-319-48927-8 035 $a(MiAaPQ)EBC4774358 035 $a(PPN)197455875 035 $a(EXLCZ)993710000001006641 100 $a20161230d2017 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aTaste and Smell /$fedited by Dietmar Krautwurst 205 $a1st ed. 2017. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2017. 215 $a1 online resource (XV, 199 p. 123 illus., 25 illus. in color.) 225 1 $aTopics in Medicinal Chemistry,$x1862-2461 ;$v23 311 $a3-319-48925-9 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aTaste receptor gene expression outside the gustatory system -- Medicinal Chemistry of Plant Naturals as Agonists/Antagonists for Taste Receptors -- Chemical activation of TRP channels in taste and smell -- Olfactory transduction channels and their modulation by varieties of volatile substances -- Chemosensory G protein-coupled receptors (GPCR) in blood leukocytes -- Neuronal functions and emerging pharmacology of TAAR1. 330 $aMedicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors. 410 0$aTopics in Medicinal Chemistry,$x1862-2461 ;$v23 606 $aMedicinal chemistry 606 $aProteins  606 $aPharmacology 606 $aMedicinal Chemistry$3https://scigraph.springernature.com/ontologies/product-market-codes/C28000 606 $aReceptors$3https://scigraph.springernature.com/ontologies/product-market-codes/L14110 606 $aPharmacology/Toxicology$3https://scigraph.springernature.com/ontologies/product-market-codes/B21007 615 0$aMedicinal chemistry. 615 0$aProteins . 615 0$aPharmacology. 615 14$aMedicinal Chemistry. 615 24$aReceptors. 615 24$aPharmacology/Toxicology. 676 $a615.19 702 $aKrautwurst$b Dietmar$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910163014603321 996 $aTaste and Smell$91562247 997 $aUNINA