LEADER 03152nam 2200445z- 450 001 9910161648003321 005 20210211 035 $a(CKB)3710000001041984 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/46652 035 $a(oapen)doab46652 035 $a(EXLCZ)993710000001041984 100 $a20202102d2016 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aEnzymes from Extreme Environments 210 $cFrontiers Media SA$d2016 215 $a1 online resource (103 p.) 225 1 $aFrontiers Research Topics 311 08$a2-88919-830-8 330 $aEnzymes are nature's biocatalysts empowered with high catalytic power and remarkable substrate specificity. Enzymes perform a wide range of functions throughout nature, and guide the biochemistry of life with great precision. The majority of enzymes perform under conditions considered normal for mesophilic, neutrophilic, terrestrial microorganisms. However, the Earth's biosphere contains several regions that are extreme in comparison, such as hypersaline lakes and pools, hydrothermal vents, cold oceans, dry deserts and areas exposed to intensive radiation. These areas are inhabited by a large number of extremophilic microorganisms which produce enzymes capable of functioning in unusual conditions. There is an increasing biotechnological and industrial demand for enzymes stable and functioning in harsh conditions, and over the past decade screening for, isolation and production of enzymes with unique and extreme properties has become one of the foremost areas of biotechnology research. The development of advanced molecular biology tools has facilitated the quest for production of enzymes with optimized and extreme features. These tools include large-scale screening for potential genes using metagenomics, engineering of enzymes using computational techniques and site-directed mutagenesis and molecular evolution techniques. The goal of this Research Topic is to present reports on latest advances in enzymes from all types of extreme environments. Contributions dealing with isolation of enzymes from extremophilic microorganisms or directly from natural environments, screening for and expression of enzymes with extreme properties using metagenomic approaches are welcome. In addition, contributions dealing with all forms of biocatalyst production and improvement are welcome, such as fermentation technology, protein engineering, directed evolution, rational design, and immobilization techniques. 606 $aBiotechnology$2bicssc 610 $aalkaliphile 610 $aBiocatalysis 610 $aBiotechnology 610 $aextremophile 610 $aExtremozyme 610 $ahalophile 610 $aindustrial enzymes 610 $apsychrophile 610 $athermophile 615 7$aBiotechnology 700 $aNoha M. Mesbah$4auth$01328933 702 $aFelipe Sarmiento$4auth 906 $aBOOK 912 $a9910161648003321 996 $aEnzymes from Extreme Environments$93039191 997 $aUNINA