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200 1 $aEarly astronomical and mathematical instruments$eA brief survey of sources and modern studies$fFrancis Maddison
205   $a[London] : [s.n.]$b1963
210   $app. 17-50$a24 cm
215   $aEstratto da: History of Science, v. 2, 1963
517  1$3UON00357694$aˆA ‰Brief survey of sources and modern studies
606   $aASTRONOMIA ISPANOARABA$3UONC021177$2FI
620   $aGB$dLondon$3UONL003044
686   $aARA XVIII$cPAESI ARABI - SCIENZE PURE E APPLICATE$2A
700  1$aMaddison$bFrancis$3UONV041905$0657074
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996   $aEarly astronomical and mathematical instruments$91170313
997   $aUNIOR

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035   $a(CKB)3710000001041991
035   $a(oapen)https://directory.doabooks.org/handle/20.500.12854/48161
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035   $a(EXLCZ)993710000001041991
100   $a20202102d2016      |y         0
101 0 $aeng
135   $aurmn|---annan
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 00$aFrontiers in the Pharmacological Manipulation of Intracellular cAMP Levels
210   $cFrontiers Media SA$d2016
215   $a1 online resource (191 p.)
225 1 $aFrontiers Research Topics
311 08$a2-88919-815-4 
330   $aCyclic adenosine monophosphate (cAMP) is a second messenger of paramount biological importance, involved in the regulation of a significant number of cellular functions through the cAMP-dependent intracellular signal transduction pathways. The aim of this "Frontiers in Pharmacology" Research Topic was to attract contributions that highlight emerging ideas in the cAMP field that: (i) describe its role in cellular function and homeostasis, (ii) present the current approaches to its pharmacological manipulation, and (iii) clarify its central role in the development of more targeted therapeutic approaches toward a spectrum of diseases. The present collection of articles highlights, in a representative (but certainly not exhaustive) way, the research activity and emerging concepts in the field, while it also reveals the therapeutic potential that targeted pharmacological manipulation of intracellular cAMP levels could exert on a number of pathological conditions.
606   $aPharmacology$2bicssc
610   $acAMP
610   $aCellular function
610   $acyclic adenosine monophosphate
610   $aDisease
610   $aHomeostasis
610   $apharmacological manipulation
610   $asignaling
610   $aTherapeutic applications
615  7$aPharmacology
700   $aGeorge S. Baillie$4auth$01291858
702   $aApostolos Zarros$4auth
702   $aFrank Christian$4auth
906   $aBOOK
912   $a9910161647303321
996   $aFrontiers in the Pharmacological Manipulation of Intracellular cAMP Levels$93022007
997   $aUNINA