LEADER 03643nam 22005655 450 001 9910158671703321 005 20200704021426.0 024 7 $a10.1007/978-4-431-56059-3 035 $a(CKB)3710000001008954 035 $a(DE-He213)978-4-431-56059-3 035 $a(MiAaPQ)EBC4778963 035 $a(PPN)198339135 035 $a(EXLCZ)993710000001008954 100 $a20170106d2017 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aCell Therapy Against Cerebral Stroke $eComprehensive Reviews for Translational Researches and Clinical Trials /$fedited by Kiyohiro Houkin, Koji Abe, Satoshi Kuroda 205 $a1st ed. 2017. 210 1$aTokyo :$cSpringer Japan :$cImprint: Springer,$d2017. 215 $a1 online resource (X, 156 p. 15 illus., 11 illus. in color.) 311 $a4-431-56057-2 311 $a4-431-56059-9 320 $aIncludes bibliographical references. 327 $aPart I. Optimal Cell Sources -- 1. Bone Marrow-Derived Mononuclear Cells -- 2. Mesenchymal Stem Cells / Bone Marrow Stromal Cells -- 3. Neural Stem Cells / Neuronal Progenitor Cells -- 4. iPS Cells / iN -- Part II. Translational Research -- 5. Cell Culture -- 6. Cell Dose, Timing and Route -- 7. Scaffold -- 8. Cell Tracking -- 9. Functional Bio-Imaging -- Part III. Clinical Trials -- 10. Review of Previous Clinical Trials and Guideline of Cell Therapy -- 11. Bone Marrow-Derived Mononuclear Cells -- 12. Mesenchymal Stem Cells. 330 $aThis book presents comprehensive reviews for both translational research and clinical trials on cell therapy for stroke. Cerebral stroke is still a leading cause of death and disability. However, despite intensive research, few treatment options are available. The therapeutic potential of cell transplantation has been studied for various pathological conditions of the central nervous system (CNS) including traumatic brain injury, traumatic spinal cord injury, degenerative disease, demyelinating disease and ischemic stroke, as the injured neural tissue in the CNS has only a limited regenerative capacity. Recently, a growing body of evidence in this field suggests that cell transplantation holds great potential as a form of stroke therapy. The authors, who are experts in the field of neurosurgery, review and discuss optimal cell sources and various issues involved in translational research; further, they outline ongoing clinical trials in Japan. 606 $aNervous system$xSurgery 606 $aNeurology 606 $aRegenerative medicine 606 $aTissue engineering 606 $aNeurosurgery$3https://scigraph.springernature.com/ontologies/product-market-codes/H39000 606 $aNeurology$3https://scigraph.springernature.com/ontologies/product-market-codes/H36001 606 $aRegenerative Medicine/Tissue Engineering$3https://scigraph.springernature.com/ontologies/product-market-codes/L16080 615 0$aNervous system$xSurgery. 615 0$aNeurology. 615 0$aRegenerative medicine. 615 0$aTissue engineering. 615 14$aNeurosurgery. 615 24$aNeurology. 615 24$aRegenerative Medicine/Tissue Engineering. 676 $a617.48 702 $aHoukin$b Kiyohiro$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aAbe$b Koji$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aKuroda$b Satoshi$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910158671703321 996 $aCell Therapy Against Cerebral Stroke$91552002 997 $aUNINA