LEADER 04350nam 22006135 450 001 9910735779203321 005 20251009073521.0 010 $a981-9911-83-4 024 7 $a10.1007/978-981-99-1183-7 035 $a(MiAaPQ)EBC30661184 035 $a(Au-PeEL)EBL30661184 035 $a(DE-He213)978-981-99-1183-7 035 $a(PPN)272255939 035 $a(CKB)27704119300041 035 $a(EXLCZ)9927704119300041 100 $a20230720d2023 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aTumor Ecosystem $eAn Ecological View of Cancer Growth and Survival /$fedited by Erwei Song 205 $a1st ed. 2023. 210 1$aSingapore :$cSpringer Nature Singapore :$cImprint: Springer,$d2023. 215 $a1 online resource (697 pages) 311 08$aPrint version: Song, Erwei Tumor Ecosystem Singapore : Springer,c2023 9789819911820 320 $aIncludes bibliographical references. 327 $aChapter 1: Interactions in cancer ecosystem -- Chapter 2: Local niche construction -- Chapter 3: Pre-metastatic niche -- Chapter 4: Emerging concepts in cluster metastasis -- Chapter 5: Neuronal regulation in cancer ecosystem -- Chapter 6: Endocrinal regulation in cancer ecosystem -- Chapter 7: Innate immune system in cancer ecosystem -- Chapter 8: Adaptive immune system in cancer ecosystem -- Chapter 9: Inflammation in cancer ecosystem -- Chapter 10: Metabolic regulation in cancer ecosystem -- Chapter 11: Vascular regulation in cancer ecosystem -- Chapter 12: Microbial interaction in cancer ecosystem -- Chapter 13: Viral interaction in cancer ecosystem -- Chapter 14: Evolution of cancer ecosystem -- Chapter 15: Driving force of cancer ecosystem -- Chapter 16: Modeling, visualizing and subtyping the cancer ecosystem -- Chapter 17: Bio-engineering methods to mimic cancer ecosystem -- Chapter 18: Cancer ecosystem-directed therapeutic strategies. 330 $aThis book intends to report new concept of onco-spheres in cancer ecosystem. Onco-spheres are defined as where cancer cells (living organisms) dynamically interact with nontumor cellular (other living organisms) and noncellular components (non-living environmental factors) in the ?host? internal environment (habitat) to construct a self-sustainable cancer ecosystem, which can be scoped at three different levels: primary/regional, distal and systemic onco-spheres. Cancer cells should be conceived as ?living organisms?, interacting with cellular or noncellular components in the host internal environment, not only with the local tumor microenvironment (TME) but also constantly communicating with a distant organ niche as well interacting with the host?s nervous, endocrine and immune systems, to construct a self-sustainable ?biosphere?, as we termed the tumor ecosystem. By looking at theinteraction of cancer and host as a unique ecosystem, we will use ecology principles to further delineate the features of the dynamics of the tumor ecosystem. As the pioneer in proposing this concept, we feel that this full-scale overview of the tumor ecosystem is able to inform the readers about this concept, and to pave the way for designing novel therapeutic strategies on actionable targets within tumor ecosystem. The book is likely to be of interest to immunologist, biologist, medical students, researchers and general public who wish to learn more on this new concept of tumor ecosystem, and how this could be applied in many fields of research. 606 $aMedicine$xResearch 606 $aBiology$xResearch 606 $aCancer 606 $aTumors$xImmunological aspects 606 $aBiomedical Research 606 $aCancer Biology 606 $aCancer Microenvironment 606 $aTumour Immunology 615 0$aMedicine$xResearch. 615 0$aBiology$xResearch. 615 0$aCancer. 615 0$aTumors$xImmunological aspects. 615 14$aBiomedical Research. 615 24$aCancer Biology. 615 24$aCancer Microenvironment. 615 24$aTumour Immunology. 676 $a616.994 702 $aSong$b Erwei 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910735779203321 996 $aTumor Ecosystem$93417153 997 $aUNINA LEADER 02516nam 22004453 450 001 9910157579703321 005 20251209084637.0 010 $a1-943772-68-1 035 $a(CKB)3710000001001728 035 $a(BIP)057412126 035 $a(MiAaPQ)EBC4819516 035 $a(Au-PeEL)EBL4819516 035 $a(CaPaEBR)ebr11358232 035 $a(OCoLC)962024266 035 $a(EXLCZ)993710000001001728 100 $a20251209d2016 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aMake Me Crazy 205 $a1st ed. 210 1$aSan Francisco :$cNYLA,$d2016. 210 4$dİ2016. 215 $a1 online resource (168 p.) 225 1 $aLoco, Texas ;$vv.2 327 $aIntro -- Copyright -- Dedication -- Chapter One -- Chapter Two -- Chapter Three -- Chapter Four -- Chapter Five -- Chapter Six -- Chapter Seven -- Chapter Eight -- Chapter Nine -- Chapter Ten -- Chapter Eleven -- Chapter Twelve -- Chapter Thirteen -- Chapter Fourteen -- Chapter Fifteen -- Chapter Sixteen -- Chapter Seventeen -- Chapter Eighteen -- Chapter Nineteen -- Chapter Twenty -- Chapter Twenty-One -- Epilogue -- Discover More by Codi Gary -- The Trouble with Attraction -- About the Author. 330 8 $a"Sassy, sexy and sweet...Codi never disappoints!" -New York Times bestselling author, Monica MurphyLoco, Texas #2A novice in the ways of men... Miranda "Rand" Coleman has seen the way love can wreck a person and wants absolutely no part of it. But when her granddaddy dies suddenly and leaves a clause in his will for her to marry or lose her inheritance, she sets her sights on the eligible men in town. But how does she snag a man if she's never learned how to set a trap?An expert in womanly wiles... Jake Hansen is the guy every woman in small town Loco, Texas wants but no one has caught. When Rand asks for his help, he figures it will be like any other scheme they've cooked up together. Once Rand lets her long brown hair down, though, Jake is suddenly seeing his best friend in a whole new light. But when it comes down to the wire, will he step up to the alter...or lose the only woman he was ever meant to love? 410 0$aLoco, Texas 517 $aLoco, Texas 610 $aFiction 700 $aGary$b Codi$01207972 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910157579703321 996 $aMake Me Crazy$93584677 997 $aUNINA