LEADER 01299nem1-2200385---450 001 990001883480403321 005 20201027132126.0 035 $a000188348 035 $aFED01000188348 035 $a(Aleph)000188348FED01 035 $a000188348 100 $a20100903d2001----km-y0itay50------ba 101 0 $aita 102 $aIT 105 $aa 000yy 120 $abbb------aa-- 121 $aaa-aabb--$b-------- 123 1 $aa$b1:25000 200 1 $aCarta geologica della regione autonoma della Sardegna$bDocumento cartografico$eMuravera$fenti realizzatori Regione Autonoma della Sardegna, Servizio geologico d'Italia 206 $a1:25000 210 $aRoma$cIstituto Poligrafico e Zecca dello Stato$d2001 215 $a4 c.$ccolor., ripieg.$d60 x 47 su foglio 87 x 57 cm, ripiegata 13 x 19 cm in cartella 16 x 22 610 0 $aSardegna$aCarte geologiche 610 0 $aCarte geologiche 676 $a551$v20$zita 710 02$aSardegna$c$05552 711 01$aServizio geologico nazionale$0434454 801 0$aIT$bUNINA$gRICA$2UNIMARC 901 $aMP 912 $a990001883480403321 952 $a60 551 B 114$b8885$fFAGBC 959 $aFAGBC 959 $aILFGE 996 $aCarta geologica della regione autonoma della Sardegna$9403630 997 $aUNINA LEADER 03397nam 2200481 450 001 9910157437903321 005 20180125150959.0 010 $a0-19-065126-1 010 $a0-19-065127-X 010 $a0-19-065125-3 035 $a(CKB)3710000001000650 035 $a(MiAaPQ)EBC4773438 035 $a(StDuBDS)EDZ0001615644 035 $a(PPN)19951044X 035 $a(EXLCZ)993710000001000650 100 $a20170110h20172017 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $2rdacontent 182 $2rdamedia 183 $2rdacarrier 200 10$aImmunity $ethe evolution of an idea /$fAlfred I. Tauber 210 1$aNew York, NY :$cOxford University Press,$d2017. 215 $a1 online resource (329 pages) 300 $aPreviously issued in print: 2017. 311 $a0-19-091419-X 311 $a0-19-065124-5 320 $aIncludes bibliographical references and index. 327 $aCover; Immunity; Copyright; Dedication; Contents; Preface; Acknowledgments; Introduction; 1. A History of the Immune Self; 2. Whither Immune Identity?; 3. Individuality Revised; 4. Immune Cognition; 5. Eco-?immunology; 6. A New Biology?; Epilogue; Notes; References; Index 330 $aImmunology is the science of biological identity. Three key characteristics?individuality, identification, and immunity?together define immune identity, and as one notion changes meaning, so do the others. The story of this mutual dependence begins with the discovery of infectious diseases, when immunity, conceived as the response to invading pathogens, focused on the infected patient?later formalized as the ?immune self.? That orientation, signifying autonomy much in line with cultural norms of individuality, dominated twentieth-century immune theory. Although an effective idiom, the self construct has proven inadequate to account for the organism?s normal physiology and exchanges with the environment. When integrated into its larger ecology, immunity?s governing model shifts from defense to the more basic cognitive function of information processing that discerns benign from the toxic. The effector function (assimilate or eliminate) only follows identification of the immune object. Moreover, as a cognitive?communicative system (analogous to the brain), the immune system?s various roles assume their full expression only when the organism is considered in its total environment??internal? and ?external.? 330 $aFrom this perspective, beyond defending an insular individual, immunity accounts for the organism?s mutualist relationships that characterize the holobiont, where lines of demarcation are blurred. In response to this ecologically informed conception of the individual, the idea of immunity correspondingly widens. 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