LEADER 03723nam 22005655 450 001 9910156338203321 005 20200705061933.0 010 $a9783319468051 024 7 $a10.1007/978-3-319-46805-1 035 $a(CKB)3710000000984041 035 $a(DE-He213)978-3-319-46805-1 035 $a(MiAaPQ)EBC4772004 035 $a(PPN)197457797 035 $a(EXLCZ)993710000000984041 100 $a20161219d2016 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aMicroarray Bioprinting Technology $eFundamentals and Practices /$fedited by Moo-Yeal Lee 205 $a1st ed. 2016. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2016. 215 $a1 online resource (XIII, 175 p. 120 illus., 114 illus. in color.) 311 $a3-319-46803-0 311 $a3-319-46805-7 320 $aIncludes bibliographical references at the end of each chapters. 327 $a1. Overview of Microarray Bioprinting Technology -- 2. Microarray Spotter and Printing Technologies -- 3. Chip Platforms and Chip Surface Treatments -- 4. Biological Sample Printing -- 5. High Content Cell Staining -- 6. 3D-Cultured Cell Image Acquisition -- 7. High-Content Image Analysis -- 8. Applications of Microarray Bioprinting. 330 $aThis book introduces key fundamentals of microarray bioprinting, including the required chip platforms and associated instruments/devices, experimental protocols for cell printing and biochemical- and cell-based assays, and several example applications. Various bioprinting approaches that allow for the rapid testing of hundreds of different cell culture conditions in combinations on a single chip are discussed in detail. Also covered is high-content, 3D cell-based imaging assays of tissue functions on miniaturized tissue constructs for high-throughput, predictive screening of drug efficacy and toxicity. This is an ideal book for graduate and postgraduate students in the field of biomedical engineering as well as scientists in the pharmaceutical industry. This book also: Broadens readers? understanding of the principles of microarray bioprinting, chip platforms and associated instruments/devices, and surface chemistry for micropatterning of cells on the chip platform Covers the latest developments in printing cells in hydrogels and methods of gelation as well as printing other biological samples in aqueous solutions Illustrates the complete process for cell staining and high-content imaging of 3D cells on the chip and predicting human metabolism and toxicology on the chip. 606 $aRegenerative medicine 606 $aTissue engineering 606 $aBiomedical engineering 606 $aBiotechnology 606 $aRegenerative Medicine/Tissue Engineering$3https://scigraph.springernature.com/ontologies/product-market-codes/L16080 606 $aBiomedical Engineering and Bioengineering$3https://scigraph.springernature.com/ontologies/product-market-codes/T2700X 606 $aMicroengineering$3https://scigraph.springernature.com/ontologies/product-market-codes/C12040 615 0$aRegenerative medicine. 615 0$aTissue engineering. 615 0$aBiomedical engineering. 615 0$aBiotechnology. 615 14$aRegenerative Medicine/Tissue Engineering. 615 24$aBiomedical Engineering and Bioengineering. 615 24$aMicroengineering. 676 $a612.028 676 $a571.538 702 $aLee$b Moo-Yeal$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910156338203321 996 $aMicroarray Bioprinting Technology$92517333 997 $aUNINA