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010   $a9783319429588
024 7 $a10.1007/978-3-319-42958-8
035   $a(CKB)3710000000964761
035   $a(DE-He213)978-3-319-42958-8
035   $a(MiAaPQ)EBC4756426
035   $a(PPN)197457282
035   $a(EXLCZ)993710000000964761
100   $a20161202d2016      u|         0
101 0 $aeng
135   $aurnn|008mamaa
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aChikungunya Virus $eAdvances in Biology, Pathogenesis, and Treatment /$fedited by Chioma M. Okeoma
205   $a1st ed. 2016.
210  1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2016.
215   $a1 online resource (X, 197 p. 39 illus., 31 illus. in color.) 
311   $a3-319-42956-6 
311   $a3-319-42958-2 
320   $aIncludes bibliographical references at the end of each chapters.
327   $aClinical Syndrome and Therapy -- Host Response and Mechanisms of Subversion of Chikungunya -- Epidemiological History of Chikungunya Virus -- Vaccines Against Chikungunya Virus Infection -- Function of Chikungunya Virus Structural Proteins -- Functions of Chikungunya Virus Nonstructural Proteins -- Interaction of Chikungunya Virus with the Mosquito Vector -- Chikungunya Virus Entry and Replication -- Chikungunya Virus-Induced Autophagy and Apoptosis -- Chikungunya Virus Pathogenesis -- Restriction Factors and Chikungunya Virus.
330   $aThe mosquito-transmitted Chikungunya virus (CHIKV) is associated with increased morbidity and debilitating chronic musculoskeletal disease in infected humans. Aedes mosquitoes, responsible for CHIKV transmission, were previously restricted to the tropical and subtropical regions of the world but increased globalization has resulted in their worldwide spread. Currently, however, there are no vaccines or effective therapies for CHIKV infection, leaving infected people to rely on their immune system to fight the disease. Chikungunya Virus: Advances in Biology, Pathogenesis, and Treatment details the exciting discoveries that have been made in various aspects of CHIKV research, including: · epidemiology · biology · mechanisms of infection and pathogenesis · host response to infection · clinical syndromes and therapy Written by leading experts, the book provides a unique resource on CHIKV, intended for researchers, clinicians, educators, public health officials, and the general public.
606   $aVirology
606   $aEpidemiology
606   $aVaccines
606   $aVirology$3https://scigraph.springernature.com/ontologies/product-market-codes/B22003
606   $aEpidemiology$3https://scigraph.springernature.com/ontologies/product-market-codes/H63000
606   $aVaccine$3https://scigraph.springernature.com/ontologies/product-market-codes/B16010
615  0$aVirology.
615  0$aEpidemiology.
615  0$aVaccines.
615 14$aVirology.
615 24$aEpidemiology.
615 24$aVaccine.
676   $a616.9101
702   $aOkeoma$b Chioma M$4edt$4http://id.loc.gov/vocabulary/relators/edt
906   $aBOOK
912   $a9910155329003321
996   $aChikungunya Virus$92597012
997   $aUNINA