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010   $a9783319483603
024 7 $a10.1007/978-3-319-48360-3
035   $a(CKB)3710000000964728
035   $a(DE-He213)978-3-319-48360-3
035   $a(MiAaPQ)EBC4748454
035   $a(PPN)197141420
035   $a(EXLCZ)993710000000964728
100   $a20161125d2017      u|         0
101 0 $aeng
135   $aurnn|008mamaa
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aCancer Biomarkers in Body Fluids $eBiomarkers in Circulation /$fby Gabriel D. Dakubo
205   $a1st ed. 2017.
210  1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2017.
215   $a1 online resource (XIX, 509 p. 20 illus. in color.) 
311   $a3-319-48359-5 
311   $a3-319-48360-9 
320   $aIncludes bibliographical references at the end of each chapters and index.
330   $aThis book examines in depth the evidence, clinical applications and potential cancer signatures in the circulation and discusses alterations in circulating cell-free nucleic acids, and circulating tumor DNA, as well as the epigenome, genome, transcriptome (coding and noncoding), proteome (both traditional serum proteins and proteomic profiles) and metabolome. Further, it highlights the clinical applications of circulating tumor cells for each cancer type and addresses the emerging importance of extracellular vesicular contents, including miRNA, oncogenes and drug resistant factors. As such, it offers a valuable reference guide for cancer researchers, oncologists, clinicians, surgeons, medical students, oncology nurses, diagnostic laboratories, and the pharmaceutical industry.
606   $aHuman genetics
606   $aOncology
606   $aCancer$xResearch
606   $aHuman Genetics$3https://scigraph.springernature.com/ontologies/product-market-codes/B12008
606   $aOncology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33160
606   $aCancer Research$3https://scigraph.springernature.com/ontologies/product-market-codes/B11001
615  0$aHuman genetics.
615  0$aOncology.
615  0$aCancer$xResearch.
615 14$aHuman Genetics.
615 24$aOncology.
615 24$aCancer Research.
676   $a611.01816
676   $a599.935
700   $aDakubo$b Gabriel D$4aut$4http://id.loc.gov/vocabulary/relators/aut$0972626
906   $aBOOK
912   $a9910155302903321
996   $aCancer Biomarkers in Body Fluids$92212304
997   $aUNINA