LEADER 04414nam 22006135 450 001 9910155301503321 005 20200705112249.0 010 $a9783319464107 024 7 $a10.1007/978-3-319-46410-7 035 $a(CKB)3710000000964796 035 $a(DE-He213)978-3-319-46410-7 035 $a(MiAaPQ)EBC4756409 035 $a(PPN)197456049 035 $a(EXLCZ)993710000000964796 100 $a20161202d2016 u| 0 101 0 $aeng 135 $aurnn#008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aPerinatal Tissue-Derived Stem Cells $eAlternative Sources of Fetal Stem Cells /$fedited by Babak Arjmand 205 $a1st ed. 2016. 210 1$aCham :$cSpringer International Publishing :$cImprint: Humana,$d2016. 215 $a1 online resource (XV, 239 p. 28 illus., 23 illus. in color.) 225 1 $aStem Cell Biology and Regenerative Medicine,$x2196-8985 311 $a3-319-46408-6 311 $a3-319-46410-8 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aPreface -- 1.Functional Dualism of Perinatal Stem Cells -- 2.Immunomodulatory Properties of Perinatal Tissue-Derived Stem Cells -- 3.Umbilical Cord Tissue and Wharton?s Jelly Mesenchymal Stem Cells Properties and Therapeutic Potential -- 4.Perinatal Tissues-Derived Endothelial Progenitor Cells -- 5.Human Amniotic Membrane as a Biological Source for Regenerative Medicine -- 6.Current Understanding Realities of Umbilical Cord Stem Cells Biology and Future Perspectives in Clinical Application -- 7.Characteristics of Mesenchymal Stem Cells Derived from Amniotic Membrane: A Potential Candidate for Stem Cell based Therapy -- 8.Amniotic Fluid: A Source of stem cells for therapeutic use and modeling of Human Genetic Diseases -- 9.cGMP-Compliant Perinatal Stem Cells -- 10.cGMP facility for clinical grade cell manufacturing: a brief review of requirements and design considerations -- 11.Ethical Issues in Perinatal Tissue Derivation and Regenerative Medicine. 330 $aThis book covers several aspects of perinatal tissue-derived stem cells, from theoretical concepts to clinical applications. Topics include functions and different sources, immunomodulatory properties, translational point of view, GMP facility design and manufacturing for clinical translation, therapeutic potentials, and finally ethical considerations. The text provides a brief review of each type of perinatal stem cells and then focuses on their multi- or pluripotent properties, regenerative capacity, and future therapeutic potential in regenerative medicine. Additionally, the book discusses GMP compliance in stem cell facilities and the manufacture of stem cells for clinical translation. The chapters are authored by world-renowned experts in the perinatal stem cell field. Perinatal Tissue-Derived Stem Cells: Alternative Sources of Fetal Stem Cells, part of Springer?s Stem Cell Biology and Regenerative Medicine series, is essential reading for basic and clinical scientists, clinicians, and pharmaceutical experts working or conducting research in the fields of stem cell biology, molecular aspects of stem cell research, tissue engineering, regenerative medicine, and cellular therapy. 410 0$aStem Cell Biology and Regenerative Medicine,$x2196-8985 606 $aStem cells 606 $aRegenerative medicine 606 $aTissue engineering 606 $aObstetrics 606 $aStem Cells$3https://scigraph.springernature.com/ontologies/product-market-codes/L16010 606 $aRegenerative Medicine/Tissue Engineering$3https://scigraph.springernature.com/ontologies/product-market-codes/L16080 606 $aObstetrics/Perinatology/Midwifery$3https://scigraph.springernature.com/ontologies/product-market-codes/H26014 615 0$aStem cells. 615 0$aRegenerative medicine. 615 0$aTissue engineering. 615 0$aObstetrics. 615 14$aStem Cells. 615 24$aRegenerative Medicine/Tissue Engineering. 615 24$aObstetrics/Perinatology/Midwifery. 676 $a571.835 702 $aArjmand$b Babak$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910155301503321 996 $aPerinatal Tissue-Derived Stem Cells$92524213 997 $aUNINA