LEADER 04061nam 2200961zu 450 001 9910155293203321 005 20210803234842.0 010 $a9783318019902 010 $a3318019909 035 $a(CKB)3780000000101138 035 $a(SSID)ssj0000578594 035 $a(PQKBManifestationID)12264686 035 $a(PQKBTitleCode)TC0000578594 035 $a(PQKBWorkID)10578792 035 $a(PQKB)10315006 035 $a(OCoLC)849647632 035 $a(SZ-BaSKA)223073 035 $a(MiAaPQ)EBC31865833 035 $a(Au-PeEL)EBL31865833 035 $a(EXLCZ)993780000000101138 100 $a20160829d1997 uy 101 0 $aeng 135 $aurunu||||| 181 $ctxt 182 $cc 183 $acr 200 00$aAntibody engineering 205 $a1st ed. 210 31$a[Place of publication not identified]$cKarger$d1997 215 $a1 online resource (XII + 212 pages) : $c 43 figures, 1 in color, 9 tables 225 1 $aIssn Series 300 $aBibliographic Level Mode of Issuance: Monograph 311 08$a9783805563567 311 08$a3805563566 327 $aCIA199706500I -- CIA19970650XI.PDF.pdf -- CIA1997065001 -- CIA1997065018 -- CIA1997065038 -- CIA1997065057 -- CIA1997065073 -- CIA1997065088 -- CIA1997065111 -- CIA1997065129 -- CIA1997065144 -- CIA1997065159 -- CIA1997065179 -- CIA1997065207. 330 $aThe last decade has witnessed remarkable developments in antibody research and its therapeutic applications. With the methods of molecular biology it is now possible to manipulate the specificities and activities of antibody molecules to generate an almost limitless array of structures for both basic investigations and the clinical setting. The contributions to this volume cover all three domains of the antibody: the variable regions, the relatively neglected but crucial hinge, and the constant region. These studies provide critical structural and functional information about antibodies, while also pointing the way to the construction of molecules with enhanced or even novel properties. Bringing together major experts on antibody engineering, this book is highly recommended to faculty, postdoctoral fellows and graduate students in molecular biology, microbiology, immunology, cancer research and genetics. 410 0$aIssn Series 606 $aBiological Science Disciplines 606 $aSerum Globulins 606 $aTechnology 606 $aImmunoproteins 606 $aGenetic Engineering 606 $aBlood Proteins 606 $aNatural Science Disciplines 606 $aGenetic Techniques 606 $aTechnology, Industry, and Agriculture 606 $aGlobulins 606 $aInvestigative Techniques 606 $aProteins 606 $aTechnology, Industry, Agriculture 606 $aDisciplines and Occupations 606 $aAmino Acids, Peptides, and Proteins 606 $aAnalytical, Diagnostic and Therapeutic Techniques and Equipment 606 $aChemicals and Drugs 606 $aImmunoglobulins 606 $aBiotechnology 606 $aProtein Engineering 615 2$aBiological Science Disciplines. 615 2$aSerum Globulins. 615 2$aTechnology. 615 2$aImmunoproteins. 615 2$aGenetic Engineering. 615 2$aBlood Proteins. 615 2$aNatural Science Disciplines. 615 2$aGenetic Techniques. 615 2$aTechnology, Industry, and Agriculture. 615 2$aGlobulins. 615 2$aInvestigative Techniques. 615 2$aProteins. 615 2$aTechnology, Industry, Agriculture 615 2$aDisciplines and Occupations 615 2$aAmino Acids, Peptides, and Proteins. 615 2$aAnalytical, Diagnostic and Therapeutic Techniques and Equipment 615 2$aChemicals and Drugs 615 2$aImmunoglobulins. 615 2$aBiotechnology. 615 2$aProtein Engineering. 702 $aCapra$b J. Donald 801 0$bPQKB 906 $aBOOK 912 $a9910155293203321 996 $aAntibody Engineering$91937003 997 $aUNINA