LEADER 01936oam 2200505I 450 001 9910154884303321 005 20230809233551.0 010 $a1-315-35536-1 010 $a1-315-37266-5 010 $a1-4822-4937-5 024 7 $a10.1201/9781315372662 035 $a(CKB)4340000000018631 035 $a(MiAaPQ)EBC4751219 035 $a(OCoLC)964698015 035 $a(EXLCZ)994340000000018631 100 $a20180331h20172017 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $2rdacontent 182 $2rdamedia 183 $2rdacarrier 200 00$aApplied surrogate endpoint evaluation methods with SAS and R /$fAriel Alonso, Theophile Bigirumurame, Tomasz Burzykowski, Marc Buyse, Geert Molenberghs, Leacky Muchene, Nolen Joy Perualila, Ziv Shkedy, Wim Van der Elst 210 1$aBoca Raton :$cCRC Press,$d[2017] 210 4$dİ2017 215 $a1 online resource (396 pages) $cillustrations 225 1 $aChapman & Hall/CRC Biostatistics Series 300 $aA Chapman and Hall book. 311 $a1-4822-4936-7 320 $aIncludes bibliographical references and index. 327 $aI. Introductory material -- II. Contemporary surrogate endpoint evaluation methods : multiple-trial methods -- III. Software tools -- IV. Additional considerations and further topics. 410 0$aChapman & Hall/CRC biostatistics series. 606 $aClinical trials$xStatistical methods 606 $aMedicine$xResearch$xMethodology 606 $aR (Computer program language) 615 0$aClinical trials$xStatistical methods. 615 0$aMedicine$xResearch$xMethodology. 615 0$aR (Computer program language) 676 $a610.72 702 $aAlonso$b Ariel$c(Statistician), 801 0$bFlBoTFG 801 1$bFlBoTFG 906 $aBOOK 912 $a9910154884303321 996 $aApplied surrogate endpoint evaluation methods with SAS and R$92172804 997 $aUNINA