LEADER 03459nam 2200505 450 001 9910795596603321 005 20230316232537.0 010 $a0-309-46266-5 010 $a0-309-46264-9 035 $a(CKB)4340000000215693 035 $a(MiAaPQ)EBC5109491 035 $a(EXLCZ)994340000000215693 100 $a20171122h20172017 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $2rdacontent 182 $2rdamedia 183 $2rdacarrier 200 00$aEnabling precision medicine $ethe role of genetics in clinical drug development : proceedings of a workshop /$fMorgan L. Boname [and four others], rapporteurs 210 1$aWashington, District of Columbia :$cThe National Academies Press,$d2017. 210 4$dİ2017 215 $a1 online resource (122 pages) $cillustrations (some color) 311 $a0-309-46263-0 320 $aIncludes bibliographical references. 327 $aIntroduction -- Overarching considerations for implementing successful genetics-enabled drug development -- Case studies in precision drug development -- Integrating genetics into the drug development pathway for complex diseases -- Finding innovative ways to integrate genetic research into the drug development process -- Reflecting back and looking forward: key themes and potential next steps in genetics-enabled drug development -- Appendix A: References -- Appendix B: Statement of task and workshop agenda -- Appendix C: Speaker biographical sketches -- Appendix D: Registered attendees. 330 1 $a"Those involved in the drug development process face challenges of efficiency and overall sustainability due in part to high research costs, lengthy development timelines, and late-stage drug failures. Novel clinical trial designs that enroll participants based on their genetics represent a potentially disruptive change that could improve patient outcomes, reduce costs associated with drug development, and further realize the goals of precision medicine. On March 8, 2017, the Forum on Drug Discovery, Development, and Translation and the Roundtable on Genomics and Precision Health of the National Academies of Sciences, Engineering, and Medicine hosted the workshop Enabling Precision Medicine: The Role of Genetics in Clinical Drug Development. Participants examined successes, challenges, and possible best practices for effectively using genetic information in the design and implementation of clinical trials to support the development of precision medicines, including exploring the potential advantages and disadvantages of such trials across a variety of disease areas. This publication summarizes the presentations and discussions from the workshop"--Publisher's description. 606 $aDrug development$vCongresses 606 $aPrecision medicine$vCongresses 606 $aPharmacogenetics$vCongresses 615 0$aDrug development 615 0$aPrecision medicine 615 0$aPharmacogenetics 676 $a615.190072 702 $aBoname$b Morgan L. 712 02$aInstitute of Medicine (U.S.).$bForum on Drug Discovery, Development, and Translation. 712 02$aRoundtable on Genomics and Precision Health. 712 02$aBoard on Health Sciences Policy. 712 02$aHealth and Medicine Division. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910795596603321 996 $aEnabling precision medicine$93690635 997 $aUNINA LEADER 03745nam 22005775 450 001 9910154845003321 005 20251214172542.0 010 $a9781484204726 010 $a1484204727 024 7 $a10.1007/978-1-4842-0472-6 035 $a(CKB)4340000000023909 035 $a(DE-He213)978-1-4842-0472-6 035 $a(MiAaPQ)EBC4767206 035 $a(CaSebORM)9781484204726 035 $a(PPN)197459307 035 $a(OCoLC)970665156 035 $a(OCoLC)ocn970665156 035 $a(EXLCZ)994340000000023909 100 $a20161208d2016 u| 0 101 0 $aeng 135 $aurnn#008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aBeginning Android Games /$fby Mario Zechner, J. F. DiMarzio, Robert Green 205 $a3rd ed. 2016. 210 1$aBerkeley, CA :$cApress :$cImprint: Apress,$d2016. 215 $a1 online resource (XXVI, 605 p. 188 illus.) 300 $aIncludes index. 311 08$a9781484204733 311 08$a1484204735 327 $a1. AN ANDROID IN EVERY HOME -- 2. FIRST STEPS WITH THE ANDROID SDK -- 3. GAME DEVELOPMENT 101 -- 4. ANDROID FOR GAME DEVELOPERS -- 5. AN ANDROID GAME DEVELOPMENT FRAMEWORK -- 6. MR. NOM INVADES ANDROID -- 7. OPENGL ES: A GENTLE INTRODUCTION -- 8. 2D GAME PROGRAMMING TRICKS -- 9. SUPER JUMPER: A 2D OPENGL ES GAME -- 10. OPENGL ES: GOING 3D -- 11. 3D PROGRAMMING TRICKS -- 12. ANDROID INVADERS: THE GRANDE FINALE -- 13. GOING NATIVE WITH THE NDK -- 14. MARKETING AND MONETIZING -- 15. PUBLISHING YOUR GAME. 330 $aLearn all of the basics needed to join the ranks of successful Android game developers. You'll start with game design fundamentals and Android programming basics, and then progress toward creating your own basic game engine and playable game apps that work on Android smartphones and tablets. Beginning Android Games, Third Edition gives you everything you need to branch out and write your own Android games for a variety of hardware. Do you have an awesome idea for the next break-through mobile gaming title? Beginning Android Games will help you kick-start your project. This book will guide you through the process of making several example game apps using APIs available in Android. What You'll Learn Gain the fundamentals of game programming in the context of the Android platform Use Android's APIs for graphics, audio, and user input to reflect those fundamentals Develop two 2D games from scratch, based on Canvas API and OpenGL ES Create a full-featured 3D game Publish your games, get crash reports, and support your users Complete your own playable 2D OpenGL games Who This Book Is For People with a basic knowledge of Java who want to write games on the Android platform. It also offers information for experienced game developers about the pitfalls and peculiarities of the platform. 606 $aComputer games?Programming 606 $aComputer programming 606 $aGame Development$3https://scigraph.springernature.com/ontologies/product-market-codes/I29040 606 $aProgramming Techniques$3https://scigraph.springernature.com/ontologies/product-market-codes/I14010 615 0$aComputer games?Programming. 615 0$aComputer programming. 615 14$aGame Development. 615 24$aProgramming Techniques. 676 $a794.8 700 $aZechner$b Mario$4aut$4http://id.loc.gov/vocabulary/relators/aut$0740128 702 $aDiMarzio$b J. F.$4aut$4http://id.loc.gov/vocabulary/relators/aut 702 $aGreen$b Robert$4aut$4http://id.loc.gov/vocabulary/relators/aut 801 0$bUMI 801 1$bUMI 906 $aBOOK 912 $a9910154845003321 996 $aBeginning Android Games$92004676 997 $aUNINA