LEADER 02702nam 2200517 450 001 9910153205803321 005 20200520144314.0 010 $a1-119-14318-7 010 $a1-119-14316-0 035 $a(CKB)3710000000960605 035 $a(MiAaPQ)EBC4751586 035 $a(DLC) 2016034126 035 $a(PPN)199264139 035 $a(Au-PeEL)EBL4751586 035 $a(CaPaEBR)ebr11307589 035 $a(CaONFJC)MIL972905 035 $a(OCoLC)965779136 035 $a(EXLCZ)993710000000960605 100 $a20160711h20172017 uy| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $2rdacontent 182 $2rdamedia 183 $2rdacarrier 200 00$aBasic pharmacokinetics and pharmacodynamics $ean integrated textbook and computer simulations /$fedited by Sara E. Rosenbaum 205 $aSecond edition. 210 1$aHoboken, New Jersey :$cJohn Wiley & Sons, Incorporated,$d[2017] 210 4$dİ2017 215 $a1 online resource (XIII, 552 pag.) $cill 311 $a1-119-14315-2 320 $aIncludes bibliographical references and index. 327 $aIntroduction to pharmacokinetics and pharmacodynamics -- Passage of drugs through membranes -- Drug administration and drug absorption / Steven Sutton -- Drug distribution -- Drug elimination and clearance -- Compartmental models in pharmacokinetics -- Pharmacokinetics of an intravenous bolus injection in a one-compartment model -- Pharmacokinetics of an intravenous bolus injection in a two-compartment model -- Pharmacokinetics of extravascular drug administration / Steven Sutton -- Introduction to noncompartmental analysis -- Pharmacokinetics of intravenous infusion in a one-compartment model -- Multiple intravenous bolus injections in the one-compartment model -- Multiple intermittent infusions -- Multiple oral doses -- Nonlinear pharmacokinetics -- Introduction to pharmacogenetics -- Models used to predict drug-drug interactions for orally administered drugs -- Introduction to physiologically based pharmacokinetic modeling -- Introduction to pharmacodynamic models and integrated pharmacokinetic--pharmacodynamic models / Diane Mould and Paul Hutson -- Semi-mechanistic pharmacokinetic--pharmacodynamic model / Diane Mould and Paul Hutson. 606 $aPharmacokinetics 606 $aComputer simulation 608 $aElectronic books. 615 0$aPharmacokinetics. 615 0$aComputer simulation. 676 $a615/.7 702 $aRosenbaum$b Sara$g(Sara E.), 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910153205803321 996 $aBasic pharmacokinetics and pharmacodynamics$92241391 997 $aUNINA